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Nonulcer dyspepsia

机译:非溃疡性消化不良

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Therapy for nonuicer dyspepsia has largely been empiric because effective therapeutic agents are sparse and therapeutic trials show inconsistent results. The Cochrane collaboration has reviewed this matter and came to the conclusion that prokinetics and acid-suppression therapy might have a significant, although small, clinical benefit over placebo. Although the role of Helicobacter pylori in nonuicer dyspepsia is still a matter of controversy, one meta-analysis suggests that in H. py/ori-positive dyspeptic patients, H, pylori eradication has a small but significant therapeutic benefit over a therapy that does not eradicate H, pylori. Other aspects of pathophysiology of nonuicer dyspepsia that have been studied in the past year include visceral hyperalgesia and abnormal sleep pattern. New studies have also investigated the clinical presentation of nonuicer dyspepsia and the possible reasons why some patients never consult a doctor whereas others do SO frequently.
机译:非癌性消化不良的治疗在很大程度上是经验性的,因为有效的治疗剂稀疏并且治疗试验显示不一致的结果。 Cochrane合作小组对此事进行了审查,得出的结论是,与安慰剂相比,动力学和抑酸疗法可能具有显着的临床益处,尽管获益很小。尽管幽门螺杆菌在非消化性消化不良中的作用仍是一个有争议的问题,但一项荟萃分析表明,在幽门螺杆菌/ ori阳性消化不良患者中,根除幽门螺杆菌比不使用幽门螺杆菌的疗法具有较小但显着的治疗益处。根除H,幽门。在过去的一年中,已研究了非肿瘤性消化不良的病理生理学的其他方面,包括内脏痛觉过敏和异常的睡眠模式。新的研究还调查了非肿瘤性消化不良的临床表现,以及某些患者从未求医而其他患者经常求医的可能原因。

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