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Celiac disease.

机译:腹腔疾病。

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摘要

Celiac disease is more prevalent than it was previously thought to be, and screening of selected population groups may reveal many new cases. Tissue transglutaminase appears to have a significant role in the degradation of gliadin and antigen production. Specific gliadin epitopes have been defined using T-cell responses. Bone disease is a significant problem for patients with celiac disease but management guidelines are being developed. Refractory sprue (nonresponsive celiac disease) appears to be a manifestation of enteropathy-associated T-cell lymphoma in most cases.
机译:腹腔疾病比以前认为的更为普遍,对选定人群的筛查可能会发现许多新病例。组织转谷氨酰胺酶似乎在麦醇溶蛋白的降解和抗原产生中具有重要作用。已经使用T细胞应答定义了特定的麦醇溶蛋白表位。对于乳糜泻患者,骨病是一个重要的问题,但是正在制定治疗指南。在大多数情况下,顽固性浇口(无反应性腹腔疾病)似乎是与肠病相关的T细胞淋巴瘤的一种表现。

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