Noninvasive tools to assess liver disease.

Clark PJ; Patel K

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Noninvasive tools to assess liver disease.

机译：用于评估肝脏疾病的非侵入性工具。

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PURPOSE OF REVIEW: To improve understanding of recent developments in the noninvasive assessment of fibrosis and their potential clinical application to a range of chronic liver diseases. RECENT FINDINGS: Many noninvasive tests have evolved from their primary validation in chronic hepatitis C virus (HCV) infection to integration into clinical management algorithms for chronic liver disease of varying cause. Recent studies consider the use of these techniques in sequence or in combination, and compare the performance of serum and imaging-based noninvasive techniques to identify patients with significant fibrosis, or those at most risk of clinical sequelae from advanced-stage disease. Methods developed in chronic hepatitis C have now been applied in different chronic liver diseases, including nonalcoholic fatty liver disease, alcoholic liver disease, HIV/HCV co-infection and primary biliary cirrhosis. A number of new management algorithms have been developed to facilitate the integration of noninvasive techniques into clinical practice. SUMMARY: Noninvasive tools to assess liver diseases continue to evolve. New imaging technologies have been developed. Existing biomarkers and imaging modalities have been better integrated into clinical practice algorithms, and applied to different chronic liver diseases. Noninvasive techniques will likely continue to be refined and play an important role in the future management of patients with chronic liver disease.

机译：审查目的：增进对纤维化的非侵入性评估及其在一系列慢性肝病中的潜在临床应用的最新进展的了解。最近的发现：许多无创性测试已经从其对慢性丙型肝炎病毒（HCV）感染的最初验证发展到了整合到针对各种原因的慢性肝病的临床管理算法中。最近的研究考虑顺序或组合使用这些技术，并比较基于血清和基于影像学的非侵入性技术的性能，以鉴定患有严重纤维化或最有可能患有晚期疾病后遗症的患者。在慢性丙型肝炎中开发的方法现已应用于各种慢性肝病，包括非酒精性脂肪肝，酒精性肝病，HIV / HCV合并感染和原发性胆汁性肝硬化。已经开发了许多新的管理算法来促进将非侵入性技术集成到临床实践中。摘要：用于评估肝脏疾病的非侵入性工具继续发展。已经开发了新的成像技术。现有的生物标志物和成像方式已更好地整合到临床实践算法中，并应用于不同的慢性肝病。无创技术可能会继续完善，并在慢性肝病患者的未来治疗中发挥重要作用。

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《Current opinion in gastroenterology》 |2011年第3期|共7页
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Clark PJ; Patel K;
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1. Noninvasive tools to assess liver disease. [J] . Clark PJ, Patel K Current opinion in gastroenterology . 2011,第3期

机译：用于评估肝脏疾病的非侵入性工具。
2. Two are better than one: noninvasive assessment of liver fibrosis in nonalcoholic fatty liver disease. [J] . Grace Lai-Hung Wong, Henry Lik-Yuen Chan Hepatology international . 2015,第4期

机译：有两个比一个更好：非酒精性脂肪肝疾病中肝纤维化的无创评估。
3. Liver: Usefulness of noninvasive biomarkers of fibrosis in chronic liver disease. [J] . Quattroni P Nature reviews. Gastroenterology & hepatology . 2011,第12期

机译：肝：纤维化的非侵入性生物标志物在慢性肝病中的作用。
4. The Project Delivery System Rating Index (PDSRI) - An Integrated Scoring Tool for Assessing Project Readiness [C] . George Cingle, John G. Wachter Iron Steel Technology Conference . 2009

机译：项目交付系统评级指数（PDSRI） - 用于评估项目准备的综合评分工具
5. Noninvasive monitoring and evaluation of local drug delivery in livers following radio frequency ablation. [D] . Exner, Agata A. 2003

机译：射频消融后无创监测和评估肝脏局部药物的递送。
6. Commentary on: Aspartate transaminase to platelet ratio index (APRI): A simple noninvasive index assessing liver fibrosis in patients with chronic liver diseases [O] . Yilei Mao, Jiuzuo Huang 2011

机译：评论：天冬氨酸转氨酶与血小板比率指数（APRI）：一种评估慢性肝病患者肝纤维化的简单无创指数
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8. Validation of Spectral Analysis as a Noninvasive Tool to Assess Autonomic Regulation of Cardiovascular Function [R] . Knapp, Charles F., Evans, Joyce M. 1996

机译：验证光谱分析作为评估心血管功能自主调节的无创工具

Noninvasive tools to assess liver disease.

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