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Gastrointestinal infections after transplantation

机译：移植后的胃肠道感染

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PURPOSE OF REVIEW: Recipients of both solid organ transplant and hematopoietic stem cell transplantation are at increased risk for infectious morbidity and mortality after transplantation due to on-going immunosuppression. Gastrointestinal infections have been increasingly reported in these populations. RECENT FINDINGS: Increased reports of gastrointestinal infections including bacterial infection with Clostridium difficile, viral infection with norovirus and parasitic pathogens like cryptosporidium are emerging. Risk factors identified have focused on type of transplant, transplant immunosuppression regimens and exposures. Although many events are self-limiting, significant morbidity and rare mortality are reported. SUMMARY: Improved diagnostic techniques have increased the reporting of several gastrointestinal infections after transplantation, affording improved understanding of the epidemiology of these diseases. Armed with this emerging data, prevention, recognition of infection and treatment strategies can be more thoroughly assessed in these at-risk populations.
机译：审查目的：由于持续的免疫抑制作用，实体器官移植和造血干细胞移植的接受者在移植后发生传染病和死亡的风险增加。在这些人群中，胃肠道感染的报道越来越多。最近的发现：胃肠道感染的报道越来越多，包括艰难梭菌的细菌感染，诺如病毒的病毒感染以及隐孢子虫等寄生性病原体。确定的危险因素集中在移植类型，移植免疫抑制方案和暴露量上。尽管许多事件是自限性的，但据报道有明显的发病率和罕见的死亡率。摘要：改进的诊断技术增加了移植后几种胃肠道感染的报道，使人们对这些疾病的流行病学有了更好的了解。有了这些新出现的数据，就可以在这些高危人群中更全面地评估预防，识别感染和治疗策略。

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