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首页> 外文期刊>Current opinion in gastroenterology >Peptic ulcer disease.
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Peptic ulcer disease.

机译：消化性溃疡病。

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PURPOSE OF REVIEW: This review attempts to contextualize some of the clinically important publications of the last 2 years as they relate to the broad topic of dyspepsia and peptic ulcer disease, both Helicobacter pylori and nonsteroidal anti-inflammatory drug-related. RECENT FINDINGS: This review includes findings which provide insight with regard to the triaging of dyspeptic subjects, information on new proton pump inhibitor drugs and H. pylori eradication 'rescue regimens'. The 'COX-2 debacle' is discussed and new data relating to the efficacy of co-therapy strategies for the prevention of nonsteroidal anti-inflammatory drug gastropathy are presented, while the use of antiplatelet agents as 'safe' substitutes for aspirin cardioprophylaxis is questioned. The important issue of proton pump inhibitor safety and nonsteroidal anti-inflammatory drug enteropathy are addressed. SUMMARY: The review provides a summary and interpretation of literature pertaining to the above issues, and should provide a point of departure for clinical decision-making relevant to these issues.
机译：审查的目的：这篇综述试图将过去两年中一些临床上重要的出版物进行背景研究，因为它们涉及消化不良和消化性溃疡疾病的广泛话题，幽门螺杆菌和与非甾体抗炎药有关。最近的发现：这篇综述包括对消化不良受试者进行分类的见解，有关新质子泵抑制剂药物和幽门螺杆菌根除“拯救方案”的信息。讨论了“ COX-2崩溃”，并提出了与联合疗法预防非甾体类抗炎药胃病的疗效有关的新数据，同时质疑使用抗血小板药作为阿司匹林心脏预防的“安全”替代品。解决了质子泵抑制剂安全性和非甾体抗炎药肠病的重要问题。摘要：审查提供了有关上述问题的文献的摘要和解释，并应为与这些问题有关的临床决策提供一个出发点。

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