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Advanced imaging of the gastrointestinal tract: research vs. clinical tools?

机译:胃肠道高级成像:研究与临床工具?

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PURPOSE OF REVIEW: Diagnostic endoscopy has moved forward considerably in the recent years. Still, three major needs have to be satisfied: endoscopy should be able to detect a lesion, characterize the lesion, and then its nature should be confirmed. These steps should ideally translate into an immediate therapeutic decision. RECENT FINDINGS: High definition endoscopy has optimized our endoscopic view onto the mucosa and can be combined with digital surface enhancement modalities. Chromoendoscopy still holds a place to detect especially flat lesions in high-risk patients such as ulcerative colitis. Digital chromoendoscopy techniques such as narrow band imaging, i-scan, or Fuji intelligent chromo endoscopy offer new possibilities of easily and reversibly obtaining enhanced tissue contrast. Autofluorescence imaging uses tissue function to yield a pseudocolored image, and has potential to serve as a red flag technique for the detection of neoplastic lesions. Confocal laser endomicroscopy has for the first time provided real time microscopy. In addition to visualizing morphology, functional and molecular imaging open new horizons for the gastroenterologist. SUMMARY: Advanced imaging techniques have provided the endoscopist with an armamentarium of novel modalities for detection, characterization and microscopy of lesions during endoscopy. In addition, functional and molecular imaging give insight into dynamic processes of tissues in their natural surroundings.
机译:审查目的:近年来,诊断性内窥镜检查取得了长足的进步。尽管如此,仍必须满足三个主要需求:内窥镜检查应能够检测到病变,表征病变,然后应确定其性质。这些步骤在理想情况下应转化为即时的治疗决策。最近的发现:高清晰度内窥镜已经优化了我们的内窥镜对粘膜的视野,可以与数字表面增强模态结合使用。内窥镜检查仍然可以发现溃疡性结肠炎等高危患者的扁平病变。诸如窄带成像,i-scan或Fuji智能型色谱内窥镜之类的数字色谱内窥镜技术为轻松而可逆地获得增强的组织对比度提供了新的可能性。自体荧光成像利用组织功能产生伪彩色图像,并且有潜力用作检测肿瘤病变的危险信号技术。共聚焦激光内镜检查首次提供了实时显微镜检查。除了可视化形态,功能和分子成像还为胃肠病学家开辟了新的视野。简介:先进的成像技术为内镜医师提供了一种新型的武器库,用于在内窥镜检查过程中对病变进行检测,表征和显微镜检查。此外,功能和分子成像可洞察自然环境中组织的动态过程。

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