Effectiveness of reactive focal mass drug administration and reactive focal vector control to reduce malaria transmission in the low malaria-endemic setting of Namibia: a cluster-randomised controlled, open-label, two-by-two factorial design trial

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Effectiveness of reactive focal mass drug administration and reactive focal vector control to reduce malaria transmission in the low malaria-endemic setting of Namibia: a cluster-randomised controlled, open-label, two-by-two factorial design trial

机译：反应性焦油群药物施用的有效性和活性局灶性载体对纳米比亚低疟疾 - 特内射击中疟疾传播的影响：簇随机控制，开放标签，双两个因子设计试验

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Background In low malaria-endemic settings, screening and treatment of individuals in close proximity to index cases, also known as reactive case detection (RACD), is practised for surveillance and response. However, other approaches could be more effective for reducing transmission. We aimed to evaluate the effectiveness of reactive focal mass drug administration (rfMDA) and reactive focal vector control (RAVC) in the low malaria-endemic setting of Zambezi (Namibia).

机译：背景技术在低疟疾 - 流行的设置，筛选和治疗密切关注指标案例，也称为无功壳检测（RACD），用于监测和反应。然而，其他方法可能更有效地减少传输。我们旨在评估反应性焦细胞群体施用（RFMDA）和活性局灶性载体对照（RAVC）在ZAMBEZI（纳米比亚）的低疟疾 - 特小环境中的有效性。

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《The Lancet》 |2020年第10233期|共13页
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正文语种 eng
中图分类医药、卫生;
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1. Effectiveness of reactive focal mass drug administration and reactive focal vector control to reduce malaria transmission in the low malaria-endemic setting of Namibia: a cluster-randomised controlled, open-label, two-by-two factorial design trial [J] . The Lancet . 2020,第10233期

机译：反应性焦油群药物施用的有效性和活性局灶性载体对纳米比亚低疟疾 - 特内射击中疟疾传播的影响：簇随机控制，开放标签，双两个因子设计试验
2. Assessing the effectiveness of household-level focal mass drug administration and community-wide mass drug administration for reducing malaria parasite infection prevalence and incidence in Southern Province, Zambia: study protocol for a community randomized controlled trial [J] . Thomas P. Eisele, Kafula Silumbe, Timothy Finn, Trials . 2015,第1期

机译：在赞比亚南部省评估家庭一级的集中大规模药物管理和社区范围内大规模药物管理对降低疟疾寄生虫感染流行率和发病率的有效性：一项社区随机对照试验的研究方案
3. Cost-Effectiveness of Focal Mass Drug Administration and Mass Drug Administration with Dihydroartemisinin-Piperaquine for Malaria Prevention in Southern Province, Zambia: Results of a Community-Randomized Controlled Trial [J] . Yukich Joshua O., Scott Callie, Silumbe Kafula, The American Journal of Tropical Medicine and Hygiene . 2020,第2期

机译：赞比亚南部省急性氨苄蛋白蛋白 - 哌啶素治疗局灶性大规模药物管理和大规模药物治疗的成本效益，对赞比亚疟疾预防：社区随机对照试验的结果
4. Ivermectin mass drug administration to humans for malaria parasite transmission control. [D] . Kobylinski, Kevin. 2011

机译：伊维菌素对人类的大规模药物管理，用于控制疟原虫的传播。
5. Study protocol for a cluster randomised controlled factorial design trial to assess the effectiveness and feasibility of reactive focal mass drug administration and vector control to reduce malaria transmission in the low endemic setting of Namibia [O] . Oliver F Medzihradsky, Immo Kleinschmidt, Davis Mumbengegwi, 2018

机译：一项集群随机对照析因设计试验的研究方案以评估纳米比亚低流行环境中反应性局灶性大剂量药物管理和媒介控制以减少疟疾传播的有效性和可行性
6. Effectiveness and safety of reactive focal mass drug administration (rfMDA) using dihydroartemisinin-piperaquine to reduce malaria transmission in very low-endemic setting of Eswatini: a pragmatic cluster randomised controlled trial [O] . Sibonakaliso Vilakati, Nontokozo Mngadi, Jade Benjamin-Chung, 2021

机译：反应性焦油群药物（RFMDA）使用二氢氨基氨素蛋白 - 稻瘟病的有效性和安全性，以减少ESWATINI的极低贫血环境中的疟疾传播：务实的簇随机对照试验

Effectiveness of reactive focal mass drug administration and reactive focal vector control to reduce malaria transmission in the low malaria-endemic setting of Namibia: a cluster-randomised controlled, open-label, two-by-two factorial design trial

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