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Liver transplantation

机译:肝移植

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摘要

Over the last 20 years dramatic improvements in liver transplantation have given children and adults a greater than 80% chance of long-term survival. The year 2002 marked a dramatic change in the system for allocating livers from a model based both on medical criteria (Child-Turcotte-Pugh) and waiting time to a system based solely on medical urgency model of end-stage liver disease (MELD). Further attempts to increase organ availability were seen in the continued increase in living donor transplants. Attention was directed both at recipient outcome and on morbidity and safety for the donor. Despite continued advances in the technical outcomes of liver transplantation, recurrent viral disease and malignancy remain major challenges.
机译:在过去的20年中,肝移植的显着改善为儿童和成人提供了80%以上的长期生存机会。 2002年标志着从基于医学标准(Child-Turcotte-Pugh)和等待时间的模型到仅基于终末期肝病医学急诊模型(MELD)的系统分配肝脏的系统发生了巨大变化。在活体供体移植的持续增加中看到了进一步提高器官利用率的尝试。注意既针对接受者的结果,也针对捐赠者的发病率和安全性。尽管肝脏移植的技术成果不断进步,但病毒性疾病复发和恶性肿瘤仍然是主要挑战。

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