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首页> 外文期刊>The Laryngoscope: A Medical Journal for Clinical and Research Contributions in Otolaryngology, Head and Neck Medicine and Surgery, Facial Plastic and Reconstructive Surgery .. >Role of voice rest following laser resection of vocal fold lesions: A randomized controlled trial
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Role of voice rest following laser resection of vocal fold lesions: A randomized controlled trial

机译：语音休息后的角色在激光切除声学折叠病变之后：随机对照试验

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Objectives/Hypothesis Voice rest is often prescribed following phonosurgery by most surgeons despite limited empiric evidence to support its practice. This study assessed the effect of postphonosurgery voice rest on vocal outcomes. Study Design Prospective, randomized controlled trial. Methods Patients with unilateral vocal fold lesions undergoing CO 2 laser excision were recruited in a prospective manner and randomized into one of two groups: 1) an experimental arm consisting of 7?days of absolute voice rest, or 2) a control arm consisting of no voice rest. The primary outcome measure was the Voice Handicap Index‐10 (VHI‐10) questionnaire. Secondary outcomes included aerodynamic measurements (maximum phonation time), acoustic measures (fundamental frequency, jitter, shimmer, and harmonic‐to‐noise ratio), and auditory‐perceptual measures. Primary and secondary outcomes were assessed preoperatively and reassessed postoperatively at the 1‐ and 3‐month follow‐up. Patient compliance to voice rest instructions were controlled for using subjective and objective parameters. Results Thirty patients were enrolled with 15 randomized to each arm of the study. Statistical analysis for the entire cohort showed a significant improvement in the mean preoperative VHI‐10 compared to postoperative assessments at 1‐month (19.0 vs. 7.3, P ?.05) and 3‐month (19.0 vs. 6.2, P ?.05) follow‐up. However, between‐group comparisons showed no significant difference in postoperative VHI‐10 at either time point. Similarly, secondary outcome measures yielded no significant difference in between‐group comparisons. Conclusions Our study shows no significant benefit to voice rest on postoperative voice outcomes as determined by patient self‐perception, acoustic variables, and auditory‐perceptual analysis. Level of Evidence 1b Clinical Trial Number NCT02788435 ( clinicaltrials.gov ) Laryngoscope , 130:1750–1755, 2020
机译：尽管有限的经验证据支持其实践，但大多数外科医生，目的/假设语音休息通常由大多数外科医生进行过帐。本研究评估了蛋解语音依赖于声乐结果的影响。研究设计前瞻性，随机对照试验。方法使用单侧声带病变的患者以前瞻性的方式招募，并随机招募到两组中的一组：1）实验臂，由7？天的绝对声音休息，或2）由NO组成的控制臂组成语音休息。主要结果措施是语音障碍指数-10（vhi-10）问卷。二次结果包括空气动力学测量（最大收听时间），声学措施（基频，抖动，闪烁和谐波对噪声比）和听觉感知措施。在术前评估初级和二次结果，并在1-和3个月的随访中术后重新评估。控制患者对语音休息说明的符合性，以使用主观和客观参数。结果30名患者注册了15名随机分别的研究。整个队列的统计分析显示平均术前vhi-10的显着改善，与术后术前术术（19.0与7.3，P＆ 05）和3个月（19.0与6.2，P＆Lt ;？05）随访。然而，组之间的比较在任一时间术后VHI-10没有显着差异。同样，次要结果测量均不产生群体比较之间的显着差异。结论我们的研究表明，由于患者自我感知，声学变量和听觉感知分析确定的术后语音结果没有显着益处。证据级别1B临床试验号NCT02788435（ClinicalTrials.gov）喉镜，130：1750-1755,2020

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