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Three‐dimensional assessment of the pharyngeal airway in Japanese preschoolers with orofacial clefts

机译:日本学龄前儿童咽气通道的三维评估orofacial leffts

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Objectives/Hypothesis Individuals with orofacial clefts often experience respiratory problems because of nasopharyngeal abnormalities. Pharyngeal airway morphology is thought to differ among the various cleft types. We measured three‐dimensional (3D) airway volume using cone‐beam computed tomography (CBCT) analysis to evaluate and compare pharyngeal airways in Japanese preschoolers with and without orofacial clefts. Study Design Retrospective case‐control study. Methods We enrolled 83 subjects (37 boys, 46 girls; mean age = 4.66 ± 0.56 years) with nonsyndromic orofacial clefts and 16 noncleft healthy subjects (seven boys, nine girls; mean age = 5.30 ± 0.52 years) as controls. The subjects were divided into five groups. Four groups were based on the cleft type: isolated cleft palate, unilateral cleft lip and alveolus), unilateral cleft lip and palate, and bilateral cleft lip and palate. The fifth group included the noncleft controls. All subjects were examined with CBCT, and the 3D airway volume was measured. We analyzed group differences statistically using analysis of covariance with the Bonferroni post hoc pairwise comparison tests for the corrected means. Results Compared with the noncleft group, each cleft group exhibited significantly decreased total and nasal airway volumes and increased superior and inferior pharyngeal airway volumes. The differences were all statistically significant. Conclusions Our findings suggest that anatomical differences exist in pharyngeal airway volumes among various cleft groups and in those without a cleft. Level of Evidence 3b Laryngoscope , 130:533–540, 2020
机译:由于鼻咽异常,具有orofacial裂缝的目标/假设常常经常经历呼吸问题。咽部气道形态被认为是各种裂缝类型的不同。我们使用锥形光束计算机断层扫描(CBCT)分析测量了三维(3D)气道体积,以评估和比较日本学龄前儿童的咽部气道,没有orofacial的裂缝。研究设计回顾性案例控制研究。方法我们注册了83名科目(37名男孩,46名女孩;平均年龄= 4.66±0.56岁)与非合适的orofacial clefts和16名非肉润健康科目(七个男孩,九名女孩;平均年龄= 5.30±0.52岁)作为对照。受试者分为五组。四组基于裂缝型:孤立的腭裂,单侧裂隙唇和肺泡,单侧裂隙唇和腭,双侧唇腭裂和腭。第五组包括非填充控制。用CBCT检查所有受试者,测量3D气道体积。我们分析了统计上的统计数据差异,使用协方差与Bonferroni后HOC成对比较测试进行了协方差的分析。结果与非甲基组相比,每个裂隙组显着降低总和鼻气量和血管总量增加,近期咽部气道体积增加。差异均有统计学意义。结论我们的研究结果表明,咽部气道在各种裂隙组中存在解剖学差异,在没有裂缝的情况下存在解剖学差异。证据水平3B喉镜,130:533-540,2020

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