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Defect repair with fibrin glue/polyglycolic acid after endoscopic laryngopharyngeal cancer resection

机译:内窥镜喉咽癌切除后用纤维蛋白胶/聚乙醇酸进行缺陷修复

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Objectives/Hypothesis In 2013, we introduced a modified technique for mucosal/muscle layer defect coverage with fibrin glue and polyglycolic acid (PGA) sheets (mMCFP technique) in patients undergoing endoscopic transoral surgeries for laryngopharyngeal cancers. This technique allows easy and convenient coverage of the wound surface, even when it involves the laryngopharyngeal lumen. To our knowledge, use of the MCFP technique for coverage of postoperative mucosal and/or muscle layer defects involving the laryngopharyngeal lumen has not been reported. The aim of the present study was to retrospectively evaluate the safety of our mMCFP technique used simultaneously with endoscopic transoral resection of Tis, T1, T2, and select T3 pharyngeal and supraglottic cancers. Study Design A single centre retrospective study. Methods Between June 2013 and February 2019, 102 patients underwent simultaneous end‐flexible‐rigidscopic transoral surgery and wound coverage using our mMCFP technique. All patients required mucosal and/or muscle layer resection. For all patients, we recorded the incidence of postoperative complications and the time period for which the PGA sheets could be observed after surgery. Results In 41%, 35%, and 8% patients, the PGA sheets could be observed on the wound surface for 2, 3, and 4?weeks, respectively. Other than postoperative bleeding in two patients (2%), no postoperative complications were recorded. Conclusions The findings of this study suggest that our mMCFP technique is a safe and simple method for the repair of mucosal and/or muscle layer defects after endoscopic transoral surgery for laryngopharyngeal cancers. Level of Evidence 4 Laryngoscope , 130:1740–1745, 2020
机译:2013年的目标/假设,我们介绍了粘膜/肌肉层缺陷覆盖的修改技术,用纤维蛋白胶和聚乙二醇(PGA)薄膜(MMCFP技术)进行喉癌癌的内窥镜传播手术患者。即使当它涉及喉咽内腔时,这种技术也可以轻松且方便地覆盖伤口表面。据我们所知,尚未报告使用MCFP技术以覆盖术后粘膜和/或涉及喉咽腔的肌肉层缺陷的覆盖。本研究的目的是回顾性评估我们的MMCFP技术的安全性,同时使用TIS,T1,T2的内窥镜传输切除,并选择T3咽部和超凡癌癌。研究设计单一中心回顾性研究。方法2013年6月至2019年2月,102例患者使用我们的MMCFP技术进行了同步结束 - 柔性 - 刚性型材手术和伤口覆盖。所有患者均需要粘膜和/或肌肉层切除。对于所有患者,我们记录了术后并发症的发生率和在手术后可以观察到PGA片的时间段。结果41%,35%和8%的患者,PGA片可以在伤口表面上观察到2,3和4周。除了两名患者的术后出血(2%),没有记录术后并发症。结论本研究的结果表明,我们的MMCFP技术是一种安全且简单的方法,用于修复喉对咽喉癌内窥镜传输手术后粘膜和/或肌肉层缺陷的方法。证据水平4喉镜,130:1740-1745,2020

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