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首页> 外文期刊>The Laryngoscope: A Medical Journal for Clinical and Research Contributions in Otolaryngology, Head and Neck Medicine and Surgery, Facial Plastic and Reconstructive Surgery .. >Computational Fluid Dynamics Analysis of Surgical Approaches to Bilateral Vocal Fold Immobility
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Computational Fluid Dynamics Analysis of Surgical Approaches to Bilateral Vocal Fold Immobility

机译：双侧声带不动的手术方法的计算流体动力学分析

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Objectives Bilateral vocal fold immobility (BVFI) is a rare and life‐threatening condition in which both vocal folds are fixed, resulting in airway obstruction associated with life‐threatening respiratory compromise. Treatment of BVFI is largely surgical and remains an unsatisfactory compromise between voice, breathing, and swallowing. No comparisons between currently employed techniques currently exist. We sought to employ computational fluid dynamics (CFD) modeling to delineate the optimal surgical approach for BVFI. Methods Utilizing clinical computed tomography of BVFI subjects, coupled with image analytics employing CFD models and subject pulmonary function data, we compared the airflow features in the baseline pathologic states and changes seen between endoscopic cordotomy, endoscopic suture lateralization, and posterior cricoid expansion. Results CFD modeling demonstrated that the greatest airflow velocity occurs through the posterior glottis on inspiration and anterior glottis on expiration in both the normal condition and in BVFI. Glottic airflow velocity and resistance were significantly higher in the BVFI condition compared to normal. Geometric indices (cross‐sectional area of airway) were lower in posterior cricoid expansion surgery when compared to alternate surgical approaches. CFD measures (airflow velocity and resistance) improved with all surgical approaches but were superior with posterior cricoid expansion. Conclusion CFD modeling can provide discrete, quantitative assessment of the airflow through the laryngeal inlet, and offers insights into the pathophysiology and changes that occur after surgery for BVFI. Level of Evidence NA. Laryngoscope , 130:E57–E64, 2020
机译：目的双边声带不动（BVFI）是一种难以和生命的危及危及生命的病症，其既有声乐折叠都是固定的，导致气道阻塞与威胁危及生命的呼吸妥协相关。 BVFI的治疗在很大程度上是手术的，仍然是语音，呼吸和吞咽之间的不令人满意的折衷。目前没有目前使用的技术之间没有比较。我们试图采用计算流体动力学（CFD）模型来描绘BVFI的最佳手术方法。方法利用BVFI受试者的临床计算机断层扫描，与采用CFD模型和对象肺功能数据的图像分析相结合，我们将基线病理状态的气流特征与内窥镜核心核心，内窥镜缝合线横向化和后部红外膨胀之间的变化进行了比较。结果CFD建模表明，最大的气流速度通过后部发光，在正常条件和BVFI中的呼气中的灵感和前射线上。与正常情况相比，BVFI条件下光流气流速度和抗性显着高。与交替手术方法相比，在后血管膨胀手术中较低的几何指数（横截面积）较低。 CFD措施（气流速度和电阻）随着所有手术方法而改善，但与后部红外膨胀优越。结论CFD建模可提供通过喉入口的气流的离散，定量评估气流，并向BVFI手术后发生的病理生理学和变化的见解。证据级别。喉镜，130：E57-E64,2020

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