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首页> 外文期刊>The Laryngoscope: A Medical Journal for Clinical and Research Contributions in Otolaryngology, Head and Neck Medicine and Surgery, Facial Plastic and Reconstructive Surgery .. >Unexpected high‐risk pathologic features following thyroidectomy in the chinese immigrant population
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Unexpected high‐risk pathologic features following thyroidectomy in the chinese immigrant population

机译：在中国移民人口中甲状腺切除术后的意外高风险病理特征

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Objective To compare rates of unexpected high‐risk pathologic features between Chinese and non‐Asian patients who underwent thyroidectomy for papillary thyroid cancer. Methods This was a retrospective cohort study at a tertiary academic urban medical center. Patients who underwent thyroidectomy for papillary carcinoma from 2015 to 2017 were included. Patient demographics, tumor characteristics, and tumor histopathology were analyzed. Primary outcome was the presence of adverse histopathologic features such as lymphovascular invasion (LVI) or microscopic/minimal extrathyroidal extension (mETE). Differences between the groups were analyzed using multivariate logistical regression analysis and propensity score‐weighted analysis. Results One hundred seventy‐nine patients were included: 58 Chinese‐born and 121 non‐Asian. The median age of the cohort was 47?years old (36–58). Twenty‐nine percent of patients were male, and 71% were female. There was no statistically significant difference between the two cohorts in rates of LVI, multifocality, extent of surgery, or presence of thyroiditis. Patients with mETE were more likely to have larger tumors ( P =?0.00247). Both the multivariate and propensity‐weighted models demonstrated that Chinese ancestry was independently associated with an increased rate of unexpected mETE (adjusted prevalence ratio, 2.52; 95% confidence interval, 1.82–3.48). Conclusion mETE is significantly higher in the immigrant Chinese compared to the non‐Asian population. Given the high prevalence of unexpected mETE in the Chinese population, the added risk of this finding should be brought into the discussion during initial surgical planning. Level of Evidence 3 Laryngoscope , 130:1844–1849, 2020
机译：目的比较中国与非亚洲患者之间意想不到的高风险的病理特点谁接受甲状腺乳头状甲状腺癌的发生率。方法这是在三级城市的学术医疗中心的一项回顾性队列研究。谁接受了甲状腺乳头状癌2015年至2017年的患者。病人的人口统计资料，肿瘤特征，和肿瘤组织病理学分析。主要的结果是不利的组织病理学的存在功能，如淋巴管浸润（LVI）或微观/最小甲状腺外分机（METE）。使用多变量逻辑回归分析和倾向评分加权分析法分析各组之间的差异。结果共79例患者纳入：58中国出生和121非亚洲。队列的年龄中位数为47？岁（36-58）。患者的百分之二十九为男性，71％为女性。有在LVI，多灶性，手术范围，或甲状腺炎的存在率两个队列之间无统计学差异显著。患者的丈量更有可能有较大的肿瘤（P =？0.00247）。无论是多变量和倾向加权模型表明，中国祖先是独立与意想不到的METE率增加（调整患病率，2.52; 95％置信区间，1.82-3.48）。结论丈量是显著较高的中国移民相比，非亚裔人口。由于意外丈量的高患病率在中国人群中，这一发现的额外风险应该在最初制定手术方案带入讨论。证据3喉镜的级别，130：1844年至1849年2020年

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