...
  • 主题
高级搜索  >
历史搜索 清空历史
首页> 外文期刊>The Laryngoscope: A Medical Journal for Clinical and Research Contributions in Otolaryngology, Head and Neck Medicine and Surgery, Facial Plastic and Reconstructive Surgery .. >From presumed benign neck masses to delayed recognition of human papillomavirus–positive oropharyngeal cancer
【24h】

From presumed benign neck masses to delayed recognition of human papillomavirus–positive oropharyngeal cancer

机译：从假定的良性颈部肿块到延迟识别人乳头瘤病毒阳性口咽癌症

获取原文
获取原文并翻译 | 示例
           
页面导航
  • 摘要
  • 著录项
  • 相似文献
  • 相关主题

摘要

Objectives/Hypothesis To describe patients with delayed diagnosis of human papillomavirus–positive oropharyngeal squamous cell carcinoma (HPV‐OPC) after initial incorrect diagnosis of branchial cleft cyst or nondiagnostic workup of unilateral neck mass. Study Design Retrospective case series. Methods Patients with delayed diagnosis of HPV‐OPC after initial nondiagnostic workup for unilateral neck mass were eligible. Medical record abstraction was performed to describe clinical characteristics at initial presentation and later diagnosis of HPV‐OPC. To estimate nodal growth rates, the short axis diameter of the lymph nodes was determined from imaging reports. Results Six patients met eligibility criteria. After a median interval of 42?months (range, 3?months–7?years) from initial presentation with unilateral neck mass, patients were diagnosed with HPV‐OPC. At the time of HPV‐OPC diagnosis, five were AJCC eighth edition overall stage I, and one was stage II. Primary tumors were T0 or T1 in the majority (83.3%, n?=?5). Among five patients with available serial imaging, despite diagnostic delay, three of five still had a single lymph node without involvement of additional nodes, whereas the remaining two developed additional suspicious nodes (ipsilateral and contralateral). Two of five developed evidence of extranodal extension. Median lymph node growth was 9.5% per year (range, ?6% to 32%). Conclusions Although the natural history of HPV‐OPC is not well understood, this case series suggests that it can be slow growing and mimic benign processes, leading to diagnostic delays. Adults presenting with neck masses should undergo complete diagnostic evaluation. Level of Evidence 4 Laryngoscope , 130:392–397, 2020
机译：目的/假设描述初始错误诊断后分支裂缝或单侧颈部质量的非诊断后延迟诊断人乳头瘤病毒阳性口咽鳞状细胞癌（HPV-OPC）的患者。研究设计回顾性案例系列。方法延迟诊断HPV-OPC后的初始非诊断后的单侧颈部质量后均有资格。进行医疗记录抽象以描述初始介绍及后来诊断HPV-OPC的临床特征。为了估计节点生长速率，从成像报告确定淋巴结的短轴直径。结果六名患者达到了资格标准。在42个月（范围，3？月7？年）的中位间隔，从单侧颈部肿块的初始介绍，患者被诊断为HPV-OPC。在HPV-OPC诊断时，五个是AJCC第八版整体阶段I，一个是II阶段。主要肿瘤在大多数（83.3％，n？= 5）中是t0或t1。在5名可用序列成像的患者中，尽管诊断延迟，但仍有三种仍然具有单个淋巴结而不参与额外节点，而剩下的两种发达的额外可疑节点（Ipsilidallal和对侧）。五个开发的外延延伸证据中的两个。中位淋巴结增长每年9.5％（范围，？6％至32％）。结论虽然HPV-OPC的自然历史尚未理解，但这种情况系列表明它可以缓慢增长和模仿良性过程，导致诊断延误。患有颈部肿块的成年人应进行完全诊断评估。证据水平4喉镜，130：392-397,2020

著录项

相似文献

  • 外文文献
  • 中文文献
  • 专利
获取原文

客服邮箱：kefu@zhangqiaokeyan.com

京公网安备：11010802029741号 ICP备案号：京ICP备15016152号-6 六维联合信息科技 (北京) 有限公司©版权所有

  • 客服微信

  • 服务号