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首页> 外文期刊>The Journal of Physiology >Cortical sensory suppression during arousal is due to the activity-dependent depression of thalamocortical synapses.
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Cortical sensory suppression during arousal is due to the activity-dependent depression of thalamocortical synapses.

机译：唤醒期间皮质感觉抑制是由于血腥突触的活性依赖性抑郁症。

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摘要

The thalamus serves as a gate that regulates the flow of sensory inputs to the neocortex, and this gate is controlled by neuromodulators from the brainstem reticular formation that are released during arousal. Here we show in rats that sensory-evoked responses were suppressed in the neocortex by activating the brainstem reticular formation and during natural arousal. Sensory suppression occurred at the thalamocortical connection and was a consequence of the activity-dependent depression of thalamocortical synapses caused by increased thalamocortical tonic firing during arousal. Thalamocortical suppression may serve as a mechanism to focus sensory inputs to their appropriate representations in neocortex, which is helpful for the spatial processing of sensory information.
机译：Thalamus用作调节对Neocortex的感觉输入流动的栅极，并且该浇口由神经调节剂免受唤醒期间释放的脑干网状形成。 在这里，我们在大鼠中展示通过激活脑干网状形成和在天然唤醒期间在Neocortex中抑制了感觉诱发的反应。 感觉抑制发生在Thalamocoricalitical联系处，是由于在唤醒期间增加了ThalamoCoric Tonic烧制而引起的ThalamoCoric突触的活性依赖性抑郁症的结果。 ThalamoCortical抑制可以用作将感觉输入聚焦到Neocortex中的适当表示的机制，这有助于感觉信息的空间处理。

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