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首页> 外文期刊>Current opinion in lipidology >Physical activity, cardiorespiratory fitness and insulin resistance: a short update.
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Physical activity, cardiorespiratory fitness and insulin resistance: a short update.

机译：身体活动，心肺适应性和胰岛素抵抗：简短更新。

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摘要

PURPOSE OF REVIEW: High levels of cardiorespiratory fitness and/or habitual physical activity are associated with reduced risk of cardiovascular disease. The responsible mechanisms are multifarious, but effects on insulin sensitivity are likely to play an important role. The purpose of this review is to highlight some recent evidence on the interrelationships between physical activity, fitness, obesity, genotype and insulin resistance. RECENT FINDINGS: Effects on cardiorespiratory fitness and abdominal obesity are both likely to contribute to the insulin-sensitizing effects of regular physical activity. Recent data suggest that at least in older adults, the intensity of an exercise intervention may influence the magnitude of changes in insulin sensitivity, and emerging data suggest that individual changes in insulin sensitivity following an exercise programme may, in part, be influenced by genotype. SUMMARY: Increasing physical activity reduces insulin resistance. As both intensity of exercise and genetic factors may modulate the magnitude of this effect, current physical activity for health guidelines that emphasize engagement in moderate-intensity physical activity in a 'one-size-fits-all' approach may need revision in the future to optimize the potential benefits accrued from individuals becoming more active.
机译：审查目的：高水平的心肺适应性和/或习惯性体育锻炼与降低心血管疾病的风险有关。负责任的机制多种多样，但对胰岛素敏感性的影响可能起重要作用。这篇综述的目的是强调一些有关体育锻炼，体能，肥胖，基因型和胰岛素抵抗之间相互关系的最新证据。最近的发现：对心肺健康和腹部肥胖的影响都可能有助于定期体育锻炼的胰岛素敏感性作用。最新数据表明，至少在老年人中，运动干预的强度可能会影响胰岛素敏感性变化的幅度，而新兴数据表明，运动计划后胰岛素敏感性的个体变化可能部分受到基因型的影响。摘要：增加体育锻炼会降低胰岛素抵抗。由于运动强度和遗传因素均可调节这种影响的程度，因此未来健康指南中强调以“一刀切”的方式从事中等强度体育锻炼的健康指导方针可能需要在未来进行修订，优化个人变得更加活跃带来的潜在利益。

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