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首页> 外文期刊>Current opinion in internal medicine >Vaccines against cervical cancer.(Miscellaneous Article)
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Vaccines against cervical cancer.(Miscellaneous Article)

机译：宫颈癌疫苗。（杂项）

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摘要

Purpose of review: The purpose of this review is to give an overview of recent developments relating to human papillomavirus vaccines and their effect on cervical cancer. Original research publications from the last year (2007) have been reviewed and summarized to present an up to date synopsis of relevant trials, and the impact they will have on clinical practice. Comparisons of the two vaccines on the market are made, and details of each are given. The effect of vaccination on men and those in the developing world is explored.Recent findings: Recent findings include results of the Females United to Unilaterally Reduce Endo/Ectocervical Disease II (FUTURE II) and PApilloma TRIal against Cancer In young Adults (PATRICIA) trials that show a significant reduction in human papillomavirus-associated anogenital disease with both quadrivalent and bivalent vaccines. The effect is greatest in women who are not yet exposed to the human papillomavirus. The international community recognizes the potential impact of this, particularly in the developing world, and strategies are being developed to try and deliver care effectively.Summary: In summary, research published in the last year has continued the initial optimistic outlook for human papillomavirus vaccination and it is likely that its effect on cervical cancer will be as promising as initially appeared.
机译：审查的目的：审查的目的是概述与人乳头瘤病毒疫苗及其对宫颈癌的影响有关的最新进展。对去年（2007年）的原始研究出版物进行了回顾和总结，以提供有关试验的最新摘要，以及它们对临床实践的影响。比较了市场上两种疫苗，并给出了每种疫苗的详细信息。最近的发现：最近的研究结果包括联合联合单方面减少子宫内膜/宫颈疾病II的女性（FUTURE II）和抗年轻人的乳头状瘤三联症（PATRICIA）试验的结果。四价和二价疫苗均能显着降低与人乳头瘤病毒相关的肛门生殖器疾病。对于尚未暴露于人乳头瘤病毒的女性，效果最大。国际社会认识到这一点的潜在影响，特别是在发展中国家，正在制定有效尝试和提供护理的战略。总结：总而言之，去年发表的研究继续对人乳头瘤病毒疫苗和它对子宫颈癌的作用可能与最初出现的一样有希望。

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