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首页> 外文期刊>Current opinion in lipidology >Prebiotics and lipid metabolism.
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Prebiotics and lipid metabolism.

机译：益生元和脂质代谢。

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Prebiotics are defined as nondigestible food ingredients that beneficially affect the host by selectively stimulating the growth or the activity of one or a limited number of bacteria (bifidobacteria, lactobacilli) in the colon. Dietary fructans are nutritionally interesting oligosaccharides that strictly conform to the definition of prebiotics and (in view of experimental studies in animals and of less numerous studies in humans) exhibit interesting serum or hepatic lipid lowering properties. Other nondigestible/fermentable nutrients, which also modulate intestinal flora activity, exhibit cholesterol or triglyceride lowering effects. Are changes in intestinal bacterial flora composition or fermentation activity responsible for those effects? What is the future of prebiotics in the nutritional control of lipidaemia and cardiovascular disease risk in humans? Those questions only receive partial response in the present review because studies of the systemic effects of prebiotics are still in their infancy, and require fundamental research devoted to elucidating the biochemical and physiological events that allow prebiotics to exert systemic effects on lipid metabolism.
机译：益生元被定义为不可消化的食品成分，可通过选择性刺激结肠中一种或有限数量的细菌（双歧杆菌，乳杆菌）的生长或活性来有益地影响宿主。膳食果聚糖是在营养上令人关注的寡糖，其严格符合益生元的定义，并且（鉴于动物的实验研究和较少的人类研究）显示出令人关注的血清或肝脂质降低特性。其他不能消化/发酵的营养物，也可以调节肠道菌群的活动，具有降低胆固醇或降低甘油三酸酯的作用。肠道细菌菌群组成或发酵活性的变化是造成这些影响的原因吗？益生元在人类脂血症的营养控制和心血管疾病风险中的前景如何？这些问题在本综述中仅得到部分答复，因为对益生元的系统性作用的研究仍处于起步阶段，需要进行基础研究以阐明允许益生元对脂质代谢发挥系统性作用的生化和生理事件。

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