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Using the tools and resources of the rcsb protein data bank

机译:使用rcsb蛋白数据库的工具和资源

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摘要

The Protein Data Bank (PDB) archive is the worldwide repository of experimentally determined three-dimensional structures of large biological molecules found in all three kingdoms of life. Atomic-level structures of these proteins, nucleic acids, andcomplex assemblies thereof are central to research and education in molecular, cellular, and organismal biology, biochemistry, biophysics, materials science, bioengineering, ecology, and medicine. Several types of information are associated with each PDBarchival entry, including atomic coordinates, primary experimental data, polymer sequence(s), and summary metadata. The Research Collaboratory for Structural Bioinformatics Protein Data Bank (RCSB PDB) serves as the U.S. data center for the PDB, distributing archival data and supporting both simple and complex queries that return results. These data can be freely downloaded, analyzed, and visualized using RCSB PDB tools and resources to gain a deeper understanding of fundamental biological processes, molecular evolution, human health and disease, and drug discovery.
机译:蛋白质数据库(PDB)档案是在世界上所有三个王国中发现的实验确定的大型生物分子三维结构的全球存储库。这些蛋白质,核酸及其复杂装配体的原子级结构对于分子,细胞和生物生物学,生物化学,生物物理学,材料科学,生物工程,生态学和医学的研究和教育至关重要。每种PDBarchival条目都有几种类型的信息,包括原子坐标,主要实验数据,聚合物序列和摘要元数据。结构生物信息学蛋白质数据库研究合作机构(RCSB PDB)充当PDB的美国数据中心,分发档案数据并支持返回结果的简单和复杂查询。可以使用RCSB PDB工具和资源免费下载,分析和可视化这些数据,以加深对基本生物学过程,分子进化,人类健康和疾病以及药物发现的了解。

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