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首页> 外文期刊>Hepatology: Official Journal of the American Association for the Study of Liver Diseases >The high burden of alcoholic cirrhosis in privately insured persons in the United States
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The high burden of alcoholic cirrhosis in privately insured persons in the United States

机译:私人被保险人在美国的酗酒肝硬化负担

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Alcoholic cirrhosis (AC) is a major cause of liver‐related morbidity and mortality in the United States. Rising rates of alcohol use disorders in the United States will likely result in more alcoholic liver disease. Our aim was to determine the prevalence, health care use, and costs of AC among privately insured persons in the United States. We collected data from persons aged 18‐64 with AC (identified by codes from the International Classification of Diseases , Ninth and Tenth Revisions) enrolled in the Truven MarketScan Commercial Claims and Encounters database (2009‐2015). We determined yearly prevalence, weighted to the national employer‐sponsored, privately insured population. Using competing risk analysis, we estimated event rates for portal hypertensive complications and estimated the association between AC and costs as well as admissions and readmissions. In 2015, 294,215 people had cirrhosis and 105,871 (36%) had AC. Mean age at AC diagnosis was 53.5 years, and 32% were women. Over the 7 years queried, estimated national cirrhosis prevalence rose from 0.19% to 0.27% ( P 0.001) and for AC from 0.07% to 0.10% ( P 0.001). Compared to non‐AC, AC enrollees were significantly more likely to have portal hypertensive complications at diagnosis and higher yearly cirrhosis and alcohol‐related admissions (25 excess cirrhosis admissions and 6.3 excess alcohol‐related admissions per 100 enrollees) as well as all‐cause readmissions. Per‐person costs in the first year after diagnosis nearly doubled for AC versus non‐AC persons (US$ 44,835 versus 23,319). Conclusion : In a nationally representative cohort of privately insured persons, AC enrollees were disproportionately sicker at presentation, were admitted and readmitted more often, and incurred nearly double the per‐person health care costs compared to those with non‐AC. (H epatology 2018).
机译:酒精性肝硬化(AC)是美国肝硬化的发病率和死亡率的主要原因。美国的酒精使用障碍率上升可能导致更酒精性肝病。我们的目标是确定美国私人被保险人的普遍存在,医疗保健和AC的费用。我们将18-64岁的人与AC(由国际疾病的国际分类的代码确定,第九和第十个修订的代码确定)注册了Truven Marketscan商业索赔和遭遇数据库(2009-2015)。我们年度普遍存在,加权国家雇主赞助,私营被保险人口。使用竞争风险分析,我们估计门户高血压并发症的事件率,并估计AC和成本与入院和入院之间的关联。 2015年,294,215人的肝硬化和105,871(36%)有AC。 AC诊断的平均年龄为53.5岁,32%是女性。在7年内询问,估计的国家肝硬化患病率从0.19%升至0.27%(P <0.001),均为0.07%至0.10%(P <0.001)。与非AC相比,AC登记者在诊断和更高年度肝硬化和酒精相关录取(25个过量的肝硬化录取和6.3每100名饮酒中有关的入学录取)以及全部原因以及全部原因以及全部原因以及全部原因的诊断和血液中有关的肠道高血压并发症入伍。诊断后的第一年的每人费用与AC与非AC人员(US $ 44,835为23,319美元)。结论:在国内代表性的私人被保险人队列,AC登记者在介绍中不成比例地令人不一致,频繁录取和预约,与非AC的人相比,每人医疗保健费用几乎翻了一番。 (2018年Hopatology)。

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