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首页> 外文期刊>Vaccine >Streptococcus pneumoniae serotype 3 is masking PCV13-mediated herd immunity in Canadian adults hospitalized with community acquired pneumonia: A study from the Serious Outcomes Surveillance (SOS) Network of the Canadian immunization research Network (CIRN)
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Streptococcus pneumoniae serotype 3 is masking PCV13-mediated herd immunity in Canadian adults hospitalized with community acquired pneumonia: A study from the Serious Outcomes Surveillance (SOS) Network of the Canadian immunization research Network (CIRN)

机译:链球菌血清菌血清型3是掩盖PCV13介导的加拿大成年人患有社区肺炎的成年人的畜牧业:一项关于加拿大免疫研究网络(CIRN)的严重结果监督(SOS)网络的研究

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摘要

Background: The 13-valent pneumococcal conjugate vaccine (PCV13) was recently shown to be effective against PCV13-type invasive pneumococcal disease (IPD) and pneumococcal community acquired pneumonia (CAP(Spn)) in healthy adults aged >= 65 years, prompting many countries to re-assess adult immunization. In Canada, the potential benefits of adult PCV13 immunization were unclear given anticipated herd immunity from PCV13 childhood immunization introduced since 2010. This study describes the serotype distribution and clinical outcomes of Canadian adults aged >= 16 years, who were hospitalized with CAP(Spn) and IPD from 2010 to 2015.
机译:背景:最近将13例肺炎球菌缀合物疫苗(PCV13)显示有效针对PCV13型侵袭性肺炎疾病(IPD)和肺炎球菌群体获得的肺炎(SPN(SPN))在健康成年人中获得> = 65岁,促使许多人 各国重新评估成人免疫。 在加拿大,成人PCV13免疫的潜在益处目前不明确于自2010年以来PCV13儿童免疫的预期畜群免疫。本研究描述了加拿大成年人的血清型分布和临床结果,= 16岁(SPN)住院治疗(SPN) 从2010年到2015年的IPD。

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