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The short-term impact of each primary dose of pneumococcal conjugate vaccine on nasopharyngeal carriage: Systematic review and meta-analyses of randomised controlled trials

机译:每种初级剂量的肺炎球菌缀合物疫苗对鼻咽携带的短期影响:随机对照试验的系统评价和荟萃分析

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摘要

Background: Early onset of persistent otitis media is a priority issue for Australian Indigenous populations. The objective is to determine the direct and short-term impact of one, two and three doses of any pneumococcal conjugate vaccine (PCV) formulation on nasopharyngeal (NP) carriage of Streptococcus pneumoniae (Spn) and non-typeable Haemophilus influenzae (NTHi), the otopathogens targeted by current PCVs.
机译:背景:持久性中耳炎的早期发作是澳大利亚土着人口的优先问题。 目的是确定一种,两种剂量的任何肺炎球菌缀合物疫苗(PCV)配方对鼻咽(NP)的直接和短期影响(PCV)制剂,肺炎链球菌(SPN)和非易型血液植物流感(NTHI), 由当前PCVs靶向的耳孢囊苷。

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