...
  • 主题
高级搜索  >
历史搜索 清空历史
首页> 外文期刊>Vaccine >The 2015–2016 influenza epidemic in Beijing, China: Unlike elsewhere, circulation of influenza A(H3N2) with moderate vaccine effectiveness
【24h】

The 2015–2016 influenza epidemic in Beijing, China: Unlike elsewhere, circulation of influenza A(H3N2) with moderate vaccine effectiveness

机译：2015 - 2016年北京甲型流感流行病：与其他地方不同，流感血液循环A（H3N2），中度疫苗效应

获取原文
获取原文并翻译 | 示例
           
页面导航
  • 摘要
  • 著录项
  • 相似文献
  • 相关主题

摘要

BackgroundWhile the 2015–2016 influenza season in the northern hemisphere was dominated by A(H1N1)pdm09 and B/Victoria viruses, in Beijing, China, there was also significant circulation of influenza A(H3N2) virus. In this report we estimate vaccine effectiveness (VE) against influenza A(H3N2) and other circulating viruses, and describe further characteristics of the 2015–2016 influenza season in Beijing.MethodsWe estimated VE of the 2015–2016 trivalent inactivated vaccine (TIV) against laboratory-confirmed influenza virus infection using the test-negative study design. The effect of prior vaccination on current VE was also examined.ResultsOf 11,000 eligible patients included in the study, 2969 (27.0%) were influenza positive. Vaccination coverage was 4.2% in both cases and controls. Adjusted VE against all influenza was 8% (95% CI: ?16% to 27%): 18% (95% CI: ?38% to 52%) for influenza A(H1N1)pdm09, 54% (95% CI: 16% to 74%) for influenza A(H3N2), and ?8% (95% CI: ?40% to 18%) for influenza B/Victoria. The overall VE for receipt of 2015–2016 vaccination only, 2014–2015 vaccination only, and vaccinations in both seasons was ?15% (95% CI: ?63% to 19%), ?25% (95% CI: ?78% to 13%), and 18% (95% CI: ?11% to 40%), respectively.ConclusionsOverall the 2015–2016 TIV was protective against influenza infection in Beijing, with higher VE against the A(H3N2) viruses compared to A(H1N1)pdm09 and B viruses.
机译：背景，2015-2016北半球的流感季节由（H1N1）PDM09和B / Victoria病毒主导，在中国北京，流感A（H3N2）病毒也有显着循环。在本报告中，我们估算患有型流感A（H3N2）和其他循环病毒的疫苗效果（VE），并描述北京2015-2016流感季节的进一步特征。近期2015-2016三价疫苗（TIV）的估计VE实验室证实流感病毒感染使用试验负面研究设计。还检查了现有疫苗接种对现行VE的影响。研究了11,000名符合条件的患者，2969（27.0％）是流感阳性。两种情况和控制中疫苗接种覆盖率为4.2％。针对所有流感的调整后8％（95％CI：？16％至27％）：流感A（H1N1）PDM09,54％（95％CI：）18％（95％CI：？38％至52％），54％（95％CI：甲型流感B / Victoria的流感A（H3N2）和1％（95％CI：？40％至18％）的16％至74％。收到2015-2016疫苗接种的总体ve，仅限2014-2015疫苗接种，以及两个季节的疫苗接种？15％（95％CI：？63％至19％），？25％（95％CI：？78 ％至13％），18％（95％CI：？11％至40％）。结论2015-2016 TIF对北京的流感感染保护，与A（H3N2）病毒相比具有更高的VE A（H1N1）PDM09和B病毒。

著录项

  • 来源
    《Vaccine》 |2018年第33期|共9页
  • 作者

    Li Zhang; Yang Pan; Volker Hackert; Wim van der Hoek; Adam Meijer; Thomas Krafft; Peng Yang; Quanyi Wang;

  • 作者单位

    Beijing Center for Disease Prevention and Control;

    Beijing Center for Disease Prevention and Control;

    Public Health Service South Limburg Department of Sexual Health Infectious Diseases and Environmental Health;

    Centre for Infectious Disease Control National Institute for Public Health and the Environment;

    Centre for Infectious Disease Control National Institute for Public Health and the Environment;

    Faculty of Health Medicine and Life Sciences Maastricht University;

    Beijing Center for Disease Prevention and Control;

    Beijing Center for Disease Prevention and Control;

  • 收录信息
  • 原文格式 PDF
  • 正文语种 other
  • 中图分类 医学免疫学;
  • 关键词

    Influenza; Vaccine effectiveness; Test-negative design; China;

    机译：流感;疫苗效果;测试负面设计;中国;

相似文献

  • 外文文献
  • 中文文献
  • 专利
获取原文

客服邮箱：kefu@zhangqiaokeyan.com

京公网安备：11010802029741号 ICP备案号：京ICP备15016152号-6 六维联合信息科技 (北京) 有限公司©版权所有

  • 客服微信

  • 服务号