...
  • 主题
高级搜索  >
历史搜索 清空历史
首页> 外文期刊>Dalton transactions: An international journal of inorganic chemistry >A novel phosphorescent iridium(III) complex bearing a donor-acceptor-type o-carboranylated ligand for endocellular hypoxia imaging
【24h】

A novel phosphorescent iridium(III) complex bearing a donor-acceptor-type o-carboranylated ligand for endocellular hypoxia imaging

机译：一种新的磷光铱（III）复合物，其轴承供体 - 受体型O-碳硼酰基化配体，用于内肠胃外缺氧成像

获取原文
获取原文并翻译 | 示例
           
页面导航
  • 摘要
  • 著录项
  • 相似文献
  • 相关主题

摘要

The structure-property relationship of carborane-embedded cationic iridium(III) complexes was investigated in this work, especially with donor-acceptor-type ligands. Firstly, an efficient synthetic approach for the new donor-acceptor-type ligands (2 and 4) was developed. By using these ligands, novel iridium(III) complexes II and IV were prepared. Complex IV shows about a 92 nm red-shift in solution (Phi(P) = 0.13 in ethanol), and the emission color has an obvious change from green to red when compared with the Model complex. In addition, the photophysical characteristics of complex IV are quite sensitive to the oxygen level in living cells, based on which endocellular hypoxia imaging of complex IV has been realized by the phosphorescence lifetime imaging microscopy (PLIM) technology. Besides the experimental studies, density functional theory (DFT) and time dependent DFT (TD-DFT) calculations have been successfully applied to investigate the excited-state electronic structures of carborane-modified iridium complexes.
机译：在这项工作中研究了碳硼嵌入式阳离子铱（III）配合物的结构 - 性质关系，特别是供体 - 受体式配体。首先，开发了新的供体型配体（2和4）的有效合成方法。通过使用这些配体，制备新的铱（III）配合物II和IV。复杂的IV在溶液（PHI（P）= 0.13中的乙醇中显示出92nm），并且与模型复合物相比，发光颜色从绿色变为红色。此外，复杂IV的光物理特征对活细胞中的氧水平非常敏感，基于磷光寿命显微镜（PLIM）技术已经实现了复杂IV的内皮缺氧成像。除了实验研究之外，已经成功地应用了密度泛函理论（DFT）和时间依赖性DFT（TD-DFT）计算以研究碳硼烷改性铱络合物的激发态电子结构。

著录项

  • 来源
  • 作者

    Li Xiang; Yin Yongheng; Gao Pengli; Li Weijie; Yan Hong; Lu Changsheng; Zhao Qiang;

  • 作者单位

    Nanjing Univ Sch Chem &

    Chem Engn State Key Lab Coordinat Chem Nanjing 210023 Jiangsu Peoples R China;

    Nanjing Univ Sch Chem &

    Chem Engn State Key Lab Coordinat Chem Nanjing 210023 Jiangsu Peoples R China;

    Nanjing Univ Posts &

    Telecommun Key Lab Organ Elect &

    Informat Displays Nanjing 210023 Jiangsu Peoples R China;

    Nanjing Univ Sch Chem &

    Chem Engn State Key Lab Coordinat Chem Nanjing 210023 Jiangsu Peoples R China;

    Nanjing Univ Sch Chem &

    Chem Engn State Key Lab Coordinat Chem Nanjing 210023 Jiangsu Peoples R China;

    Nanjing Univ Sch Chem &

    Chem Engn State Key Lab Coordinat Chem Nanjing 210023 Jiangsu Peoples R China;

    Nanjing Univ Posts &

    Telecommun Key Lab Organ Elect &

    Informat Displays Nanjing 210023 Jiangsu Peoples R China;

  • 收录信息
  • 原文格式 PDF
  • 正文语种 eng
  • 中图分类 化学;无机化学;
  • 关键词

相似文献

  • 外文文献
  • 专利
获取原文

客服邮箱：kefu@zhangqiaokeyan.com

京公网安备：11010802029741号 ICP备案号：京ICP备15016152号-6 六维联合信息科技 (北京) 有限公司©版权所有

  • 客服微信

  • 服务号