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Dysglycemia and the Density of the Coronary Vasa Vasorum

机译：脱节性血症和冠状动脉vasoRum的密度

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OBJECTIVE This study was conducted to determine the relationship between dysglycemia and the coronary artery vasa vasorum density. RESEARCH DESIGN AND METHODS The left anterior descending coronary artery was removed from 57 deceased individuals during autopsy, and the capillaries in the vessel wall were identified using fluorescent immunohistochemical staining. HbA(1c) was determined in postmortem whole blood for each individual. The density of the vasa vasorum in the intima-media and the adventitia was manually quantified and recorded by readers unaware of the individual's other characteristics. RESULTS The individuals with diabetes had a lower density of the coronary vasa vasorum than those without diabetes. The higher the HbA(1c), the lower the density of these vessels in the adventitia and entire vessel wall. CONCLUSIONS Dysglycemia-induced damage to the vasa vasorum may promote ischemic heart disease in people with diabetes.
机译：目的进行该研究以确定脱糖血症与冠状动脉VASORUM密度之间的关系。 研究设计和方法在尸检中从57名死者中除去左前期下降冠状动脉，并使用荧光免疫组织化学染色鉴定血管壁的毛细血管。 HBA（1C）在淘汰全血中测定每个人。 在内部培养基和外膜中的vasa血管血管血管瘤的密度被手动量化，并通过读者不知道个人的其他特征来记录。 结果糖尿病的个体具有冠状动脉VASA血管的密度低于没有糖尿病的血管血管。 HBA（1C）越高，在复位和整个血管壁中较低的这些血管的密度越低。 结论Dysglycemia诱导的Vasa Vasorum损伤可能促进糖尿病人的缺血性心脏病。

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