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首页> 外文期刊>Diabetes care >The 2018 AHA/ACC/AACVPR/AAPA/ABC/ACPM/ADA/AGS/APhA/ASPC/NLA/PCNA* Guidelines on the Management of Blood Cholesterol in Diabetes
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The 2018 AHA/ACC/AACVPR/AAPA/ABC/ACPM/ADA/AGS/APhA/ASPC/NLA/PCNA* Guidelines on the Management of Blood Cholesterol in Diabetes

机译:2018年AHA / ACC / AACVPR / AAPA / ABC / ACPM / ADA / AGS / APHC / NLA / PCNA *糖尿病血液胆固醇管理指南

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摘要

The American College of Cardiology/American Heart Association Task Force on Clinical Practice Guidelines recently published its 2018 recommendations on management of LDL cholesterol (LDL-C) in people with diabetes. For primary prevention, moderate-intensity statin therapy is recommended for those aged 40-75 years, with a preference for high-intensity statin treatment for older subjects and for those with higher estimated risk or risk-enhancing factors following a patient-clinician discussion. Statin therapy may be reasonable in adults 75 years of age where there is less evidence for benefit. For people with diabetes and established atherosclerotic cardiovascular disease, high-intensity statin therapy is recommended. The majority of these subjects have very high risk, and an LDL-C goal of <70 mg/dL is recommended. If this target is not achieved, ezetimibe and/or a proprotein convertase subtilisin/kexin type 9 inhibitor may be added.
机译:美国心脏病学 - 美国心脏病学院校临床实践指南最近发表了关于糖尿病人类LDL胆固醇(LDL-C)的2018年推荐。 对于初级预防,建议适用于40-75岁以上的中等强度汀类药物治疗,优先考虑患者临床医生讨论后较旧的受试者的高强度他汀类药物治疗和具有较高估计风险或风险增强因素的调节。 他汀类药物治疗可能是75岁的成年人的合理,其中有劣势的证据。 对于患有糖尿病和建立动脉粥样硬化的心血管疾病的人,建议使用高强度汀类药物治疗。 这些受试者的大多数具有很高的风险,建议使用<70 mg / dl的LDL-C目标。 如果未实现该目标,则可以加入ezetimibe和/或先前转化酶枯草杆菌蛋白酶/ kexin型9抑制剂。

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