Targeted peripheral analgesics therapy for neuropathic pain.

Argoff CE

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Targeted peripheral analgesics therapy for neuropathic pain.

机译：针对神经性疼痛的靶向外周镇痛药治疗。

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The term targeted peripheral analgesics has been suggested to describe analgesics with a mechanism of action that appears to be primarily through reducing pain transmission within the peripheral nervous system. Key differences between targeted peripheral (topical) and systemic analgesics and the difference between topical and transdermal analgesics are discussed in this article. A review of the clinical conditions, which have been reported to respond to targeted peripheral analgesics, also is described in detail.

机译：已经提出了术语“靶向外周镇痛药”来描述具有作用机制的镇痛药，该作用机制似乎主要是通过减少周围神经系统内的疼痛传播。本文讨论了靶向外周（局部）和全身镇痛药之间的主要区别以及局部和透皮镇痛药之间的区别。还详细描述了对据报道对靶向外周镇痛药有反应的临床情况的综述。

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《Current pain and headache reports.》 |2004年第3期|共6页
作者
Argoff CE;
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正文语种 eng
中图分类治疗学;
关键词
Analgesics; Neuralgia; Peripheral Nervous System; 镇痛药; 神经痛; 周围神经系统;

机译：Analgesics;Neuralgia;Peripheral Nervous System;镇痛药;神经痛;周围神经系统;

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1. Targeted peripheral analgesics therapy for neuropathic pain. [J] . Argoff CE Current pain and headache reports. . 2004,第3期

机译：针对神经性疼痛的靶向外周镇痛药治疗。
2. Microglial Ca(2+)-activated K(+) channels are possible molecular targets for the analgesic effects of S-ketamine on neuropathic pain. [J] . Hayashi Y, Kawaji K, Sun L, The Journal of Neuroscience: The Official Journal of the Society for Neuroscience . 2011,第48期

机译：小胶质细胞Ca（2+）激活的K（+）通道是S-氯胺酮对神经性疼痛的镇痛作用的可能分子靶标。
3. Percutaneous electrical nerve stimulation: a novel analgesic therapy for diabetic neuropathic pain. [J] . Hamza MA, White PF, Craig WF, Diabetes care . 2000,第3期

机译：经皮电神经刺激：一种针对糖尿病性神经性疼痛的新型镇痛疗法。
4. Peripheral Glutamate Receptors: Novel Targets for Analgesics? [C] . Susan M. Carlton, Terry A. McNearney, Brian E. Cairns World Congress on Pain . 2003

机译：外周谷氨酸受体：镇痛药的新靶点？
5. Blockade of ectopic activity at the initial stage of peripheral nerve injury prevents neuropathic pain. [D] . Xie, Wenrui. 2003

机译：在周围神经损伤的初始阶段，异位活性受阻可预防神经性疼痛。
6. Alterations in endocannabinoid tone following chemotherapy-induced peripheral neuropathy: Effects of endocannabinoid deactivation inhibitors targeting fatty-acid amide hydrolase and monoacylglycerol lipase in comparison to reference analgesics following cisplatin treatment [O] . Josée Guindon, Yvonne Lai, Sara M. Takacs, -1

机译：化疗诱导的外周神经病变后内胆碱蛋白调的改变：内胆蛋白去激活抑制剂的影响靶向脂肪酸酰胺水解酶和单酰基甘油脂肪酶的参考镇痛药如顺铂治疗
7. Molecular mechanisms underlying the enhanced analgesic effect of oxycodone compared to morphine in chemotherapy-induced neuropathic pain. [O] . Karine Thibault, Bernard Calvino, Isabelle Rivals, 2014

机译：与吗啡相比，羟考酮在化疗引起的神经性疼痛中增强镇痛作用的分子机制。
8. MC5-A Scrambler Therapy for the Treatment of Chronic Neuropathic Extremity Pain. [R] . 2017

机译：mC5-a scrambler疗法治疗慢性神经性肢体疼痛。

Targeted peripheral analgesics therapy for neuropathic pain.

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