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首页> 外文期刊>Journal of Agricultural and Food Chemistry >Preparation of an Environmentally Friendly Formulation of the Insecticide Nicotine Hydrochloride through Encapsulation in Chitosan/Tripolyphosphate Nanoparticles
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Preparation of an Environmentally Friendly Formulation of the Insecticide Nicotine Hydrochloride through Encapsulation in Chitosan/Tripolyphosphate Nanoparticles

机译：通过在壳聚糖/三聚磷酸磷酸纳米粒子中包封，制备盐酸杀虫剂尼古丁尼古丁的环保制剂

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摘要

Insecticide nicotine hydrochloride (NCT) was formulated as nanoparticles composed of chitosan (CS) and sodium tripolyphosphate (TPP) to undermine its adverse impacts on human health and reinforce its physicochemical stability. The study investigated the preparation and characterization of chitosan/tripolyphosphate nanoparticles (CS/TPP NPs) with good encapsulation efficiency (55%), uniform morphology, and physicochemical stability (45 days) through dynamic light scattering (DLS), transmission electron microscopy (TEM), and small-angle X-ray scattering (SAXS) measurements. A bioassay against Musca domestica NCT CS/TPP NPs exhibited good bioactivity and thermal stability. The effect of the monovalent salt (NaCl) on manipulating the formation and size distribution of ionically cross-linked nanoparticles was demonstrated as well. The formulation of NCT CS/TPP NPs could be a utility candidate in public health and agriculture.
机译：盐酸尼古丁尼古丁（NCT）配制为由壳聚糖（CS）和三聚磷酸钠（TPP）组成的纳米颗粒，以破坏其对人体健康的不利影响，并加强其物理化学稳定性。 该研究研究了通过动态光散射（DLS），透射电子显微镜（TEM ）和小角度X射线散射（萨克斯）测量。 针对Musca的生物测定法为NCT CS / TPP NPS表现出良好的生物活性和热稳定性。 还证实了单价盐（NaCl）对操纵离子交联纳米颗粒的形成和尺寸分布的影响。 NCT CS / TPP NPS的制定可能是公共卫生和农业的实用候选人。

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