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首页> 外文期刊>Journal of Applied Polymer Science >Hydrogel wound dressings based on chitosan and xyloglucan: Development and characterization
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Hydrogel wound dressings based on chitosan and xyloglucan: Development and characterization

机译：基于壳聚糖和木糖葡聚糖的水凝胶伤口敷料：发展与表征

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摘要

Xyloglucan is a polysaccharide isolated from chia seed gum (Salvia hispanica L.) and can act as a soluble fiber. In this investigation, several porous hydrogels were prepared from mixtures of chitosan and xyloglucan. To characterize these biomaterials, their mechanical, hydrophilic, structural, and morphological properties were measured, as well as their biodegradability and antimicrobial activity. The pore sizes of the porous hydrogels were 32.8-101.6 mu m, and their water retention capacity is proportional to the added amount of xyloglucan. Dynamic degradation of the porous hydrogels with lysozymes showed progressive weight loss during the 14 days of testing. The mechanical properties improved slightly after the addition of xyloglucan. All of these results indicate that the incorporation of vegetable-derived polymers such as xyloglucan improves the properties of chitosan without affecting its antimicrobial capacity. Thus, biomaterials based on chitosan and xyloglucan are a promising option for the design of hydrogel wound dressings for medical applications. (c) 2018 Wiley Periodicals, Inc. J. Appl. Polym. Sci. 2019, 136, 47342.
机译：Xyloglucan是从Chia Seed Gum（Salvia Hispanica L）中分离的多糖，并可作为可溶性纤维。在该研究中，由壳聚糖和木糖葡聚糖的混合物制备几种多孔水凝胶。为了表征这些生物材料，测量其机械，亲水，结构和形态学性质，以及它们的生物降解性和抗微生物活性。多孔水凝胶的孔径为32.8-101.6μm，它们的水保持能力与含有木葡聚糖的添加量成比例。用溶菌酶的多孔水凝胶的动态降解显示在测试后的14天内进行逐步减肥。在添加木瓜葡聚糖后，机械性能略微改善。所有这些结果表明，掺入植物衍生的聚合物如木葡聚糖，改善了壳聚糖的性质，而不会影响其抗微生物能力。因此，基于壳聚糖和木葡聚糖的生物材料是用于医疗应用的水凝胶伤口敷料的有希望的选择。 （c）2018 Wiley期刊，Inc.J.Phill。聚合物。 SCI。 2019,136,47342。

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