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首页> 外文期刊>Journal of Applied Polymer Science >Comparison of prolonged antibacterial activity and release profile of propolis-incorporated PVA nanofibrous mat, microfibrous mat, and film
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Comparison of prolonged antibacterial activity and release profile of propolis-incorporated PVA nanofibrous mat, microfibrous mat, and film

机译：蜂胶掺入PVA纳米纤维垫，微纤维垫和薄膜的长期抗菌活性和释放曲线的比较

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摘要

Propolis as a natural antibacterial agent was incorporated into the poly(vinyl alcohol) (PVA) in different forms of nanofiber, microfiber, and film. The successful fabrication of uniform nanofibers with 85-314 nm diameters and microfibers with 2.02 m diameter was proved by scanning electron microscopy. Structural analysis by Fourier transform infrared spectroscopy and X-ray diffraction and swelling properties confirmed the formation PVA hydrogel and its H-bonding to the propolis. Evaluation and comparison of antimicrobial properties of produced samples against Staphylococcus aureus strains revealed that nanofiber mat with 19 mm inhibition zone has 11.76 and 26.67% higher efficiency against bacteria than microfiber mat and film with 17 and 15 mm inhibition zone, respectively. Nanofibrous mat showed sustained release during 96 h by maintaining full antibacterial activity up to 51 h which is of great importance in burn wounds. These results confirm the advanced performance of natural propolis in the form of nanofiber substrate as wound dressing. (c) 2017 Wiley Periodicals, Inc. J. Appl. Polym. Sci. 2018, 135, 45794.
机译：蜂胶作为天然抗菌剂掺入聚（乙烯醇）（PVA）中以不同形式的纳米纤维，微纤维和薄膜。通过扫描电子显微镜证明，通过扫描电子显微镜成功制造具有85-314nm直径的均匀纳米纤维和2.02μm直径的微纤维。傅立叶变换红外光谱和X射线衍射和溶胀性能的结构分析证实了形成PVA水凝胶及其与蜂胶的H键合。对金黄色葡萄球菌菌株产生样品的评价和比较，抑制带有19mm的纳米纤维垫的纳米纤维垫具有比微纤维垫和17和15mM抑制区的微纤维垫和膜更高的效率增加了11.76％和26.67％。纳米纤维垫通过维持全抗菌活性至51小时，在96小时内显示持续释放，这在烧伤伤口中具有重要意义。这些结果证实了纳米纤维衬底形式的天然蜂胶的高级性能作为伤口敷料。 （c）2017 Wiley期刊，Inc.J.Phill。聚合物。 SCI。 2018,135,45794。

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