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首页> 外文期刊>Journal of Applied Polymer Science >Preparation of antibacterial temperature-sensitive silver-nanocomposite hydrogels from N-isopropylacrylamide with green tea
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Preparation of antibacterial temperature-sensitive silver-nanocomposite hydrogels from N-isopropylacrylamide with green tea

机译：用绿茶制备抗菌温度敏感银纳米复合水凝胶的抗菌 - 丙烯酰胺

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摘要

This article reports the temperature-sensitive, green tea (GT)-based silver-nanocomposite hydrogels for bacterial growth inactivation. The temperature-sensitive hydrogels were prepared via free-radical polymerization using temperature-sensitive N-isopropylacrylamide (NIPAM) monomer with GT as the hydrogel matrix. The nanocomposite hydrogels were encapsulated with silver ions via swelling method, which was later reduced to silver nanoparticles using Azadirachta indica leaf extract. The temperature-sensitive silver nanocomposite hydrogels were analyzed by using Fourier transforms infrared, UV-visible spectroscopy, differential scanning calorimetry-thermogravimetric analysis, X-ray diffraction, scanning electron microscopy, and transmission electron microscopy. The prepared hydrogels exhibited higher phase volume transition temperature than the NIPAM. The inhibition zone study of the inactivation of bacteria on the developed hydrogels was carried out against Gram negative (Escherichia coli) and Gram positive (Staphylococcus aureus), which revealed that the prepared hydrogels are helpful for the inactivation of these bacteria due to the high stabilization of antibacterial properties of the silver nanoparticles. The developed hydrogels are promising for biomedical applications. (c) 2017 Wiley Periodicals, Inc. J. Appl. Polym. Sci. 2018, 135, 45739.
机译：本文报道了用于细菌生长失活的温度敏感的绿茶（GT）的银纳米复合水凝胶。通过使用具有GT作为水凝胶基质的温度敏感的N-异丙基丙烯酰胺（NIPAM）单体，通过自由基聚合制备温度敏感水凝胶。通过溶胀法将纳米复合水凝胶用银离子包封，其后来使用Azadirachta indeca叶提取物减少到银纳米粒子。通过使用傅里叶变换红外线，UV可见光谱，差示扫描量热法 - 热重分析，X射线衍射，扫描电子显微镜和透射电子显微镜分析温度敏感银纳米复合水凝胶。制备的水凝胶表现出比NIPAM更高的相体积转变温度。对发育水凝胶上的细菌失活的抑制区研究对革兰氏阴性（大肠杆菌）和克阳性（金黄色葡萄球菌）进行，这表明制备的水凝胶是有助于由于高稳定而导致这些细菌的灭活银纳米粒子的抗菌性质。开发的水凝胶是对生物医学应用的希望。 （c）2017 Wiley期刊，Inc.J.Phill。聚合物。 SCI。 2018,135,45739。

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