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首页> 外文期刊>Journal of Applied Polymer Science >Reliable surface modification of dental plastic substrates to reduce biofouling with a photoreactive phospholipid polymer
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Reliable surface modification of dental plastic substrates to reduce biofouling with a photoreactive phospholipid polymer

机译：牙科塑料基材的可靠表面改性，以减少光反应性磷脂聚合物的生物污染

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摘要

Plastic substrates have been widely applied in clinical settings for dental treatments. These substrates should be strong enough for long-term implantation in the oral cavity and should be resistant to biofouling. We developed a new photoreactive phospholipid polymer to reduce biofouling on dental plastics via a photochemical reaction. Poly(methyl methacrylate) (PMMA) and poly(ether ether ketone) (PEEK) were used as dental plastics. To determine the antibiofouling properties on the polymer surface, the phospholipid polymer was covalently immobilized on the substrates by UV irradiation. We evaluated the antibiofouling properties by observing the protein adsorption and cell and bacterial adhesion. Significant protein adsorption and cell adhesion appeared on the bare PMMA and PEEK substrates but decreased dramatically after surface modification with the phospholipid polymer. Thus, this photoreactive polymer shows potential for conferring dental plastics with antibiofouling properties. (c) 2018 Wiley Periodicals, Inc. J. Appl. Polym. Sci. 2018, 135, 46512.
机译：塑料基材已广泛应用于牙科治疗的临床环境中。这些基材足以足够强，可用于在口腔中长期植入，并且应该抵抗生物污垢。我们开发了一种新的光反应性磷脂聚合物，通过光化学反应减少牙科塑料的生物污垢。聚（甲基丙烯酸甲酯）（PMMA）和聚（醚醚酮）（PEEK）用作牙科塑料。为了确定聚合物表面上的抗偏心性质，通过UV辐射将磷脂聚合物共价固定在基材上。通过观察蛋白质吸附和细胞和细菌粘附，我们评估了抗困难性质。在裸PMMA和PEEK基材上出现显着的蛋白质吸附和细胞粘附，但在用磷脂聚合物表面改性后显着降低。因此，这种光反应性聚合物显示出赋予牙科塑料的可能性抗牙龈特性。 （c）2018 Wiley期刊，Inc.J.Phill。聚合物。 SCI。 2018,135,46512。

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