• 主题
高级搜索  >
历史搜索 清空历史
首页> 外文期刊>Journal of Applied Polymer Science >Synthesis and Characterization of the Core-Shell Magnetic Molecularly Imprinted Polymer Nanoparticles Using 2-(Methacrylamido)ethyl Methacrylate Amide as a Novel Cross-Link Agent for Controlled Release of Betamethasone
【24h】

Synthesis and Characterization of the Core-Shell Magnetic Molecularly Imprinted Polymer Nanoparticles Using 2-(Methacrylamido)ethyl Methacrylate Amide as a Novel Cross-Link Agent for Controlled Release of Betamethasone

机译：使用2-（甲基丙烯酰胺酰胺酰胺）甲基丙烯酸甲基丙烯酰胺甲基丙烯酸乙酯的核 - 壳磁性分子印迹聚合物纳米粒子的合成与表征作为脂肪醇释放的新型交联剂

获取原文
获取原文并翻译 | 示例
           
页面导航
  • 摘要
  • 著录项
  • 相似文献
  • 相关主题

摘要

Novel magnetic molecularly imprinted polymer nanoparticles (MMIPs) using 2-(methacrylamido) ethyl methacrylate amide (MAEMA) as a cross linker and super paramagnetic core-shell nanoparticle as a supporter for use in controlled release were prepared by precipitation polymerization. A novel cross-linking agent was synthesized by the reaction of methacryloyl chloride with p-phenylenediamine. The Fe3O4 nanoparticles were encapsulated with a SiO2 shell and functionalized with ACH@CH2 and MMIPs were prepared using methacrylic acid as a functional monomer, MAEMA as a cross-linker, and betamethasone as a template. Magnetic nonmolecularly imprinted polymers (MNIPs) were also synthesized with the same synthesis procedure of MMIPs but without the presence of the template. The obtained MMIPs were characterized using transmission electron microscopy, dynamic light scattering, Fourier transform infrared spectroscopy (FTIR), X-ray diffraction, and the vibrating sample magnetometer techniques. The performance of the MMIPs for the controlled release of betamethasone was assessed and results showed that the magnetic MIPs also have possible applications in sustained drug release. (C) 2014 Wiley Periodicals, Inc.
机译：通过沉淀聚合制备使用2-（甲基丙烯酰胺酰胺）甲基丙烯酸乙酯（MAEMA）作为交叉连接器和超顺磁性核 - 壳纳米粒子的新型磁性分子印迹聚合物纳米颗粒（MMIP）作为用于控制释放的载体，以用于控制释放。通过用对苯二胺的甲基丙烯酰氯的反应合成了一种新的交联剂。四氧化三铁纳米颗粒包封在SiO 2壳，并用ACH @ CH2官能化并用甲基丙烯酸作为功能性单体，作为梅马交联剂，和倍他米松作为模板制备MMIPs。磁性非分子印迹聚合物（MNIPS）也用MMIPS的相同合成方法合成，但不存在模板。使用透射电子显微镜，动态光散射，傅里叶变换红外光谱（FTIR），X射线衍射和振动样品磁力仪技术，所获得的MMIP。评估MMIPS用于受控释放倍甲醇塞泊酮的性能，结果表明，磁力MIPS还具有持续的药物释放中可能的应用。 （c）2014 Wiley期刊，Inc。

著录项

相似文献

  • 外文文献
  • 中文文献
  • 专利
获取原文

客服邮箱：kefu@zhangqiaokeyan.com

京公网安备：11010802029741号 ICP备案号：京ICP备15016152号-6 六维联合信息科技 (北京) 有限公司©版权所有

  • 客服微信

  • 服务号