首页> 外文期刊>Journal of Applied Polymer Science >Comparative analysis of PVA hydrogels incorporating two natural antimicrobials: Punica granatum and Arnica montana tinctures
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Comparative analysis of PVA hydrogels incorporating two natural antimicrobials: Punica granatum and Arnica montana tinctures

机译:PVA水凝胶的比较分析掺入两种天然抗菌剂:Punica Granatum和Arnica Montana酊剂

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摘要

Poly(vinyl alcohol) (PVA) hydrogels are biocompatible materials that retain relatively high amounts of aqueous fluids in their network. The incorporation of antimicrobial natural products, such as pomegranate and arnica, is a strategy for coupling their bactericidal effects with the favorable properties of the gels for wound healing treatment. The goal of this work was to investigate the microstructural, mechanical, and release properties of PVA-pomegranate and PVA-arnica samples. Physical interactions were observed by Fourier transform infrared spectra in PVA-pomegranate samples. The addition of pomegranate to PVA led to high T-g, probably related to the physical interactions, and low T-m and X-c, possibly due to the pomegranate location between PVA chains. Increased levels of arnica were associated with a slight decrease in samples' X-c, probably due to a physical barrier imposed by arnica to the interaction of PVA chains. PVA samples presented higher swelling than the samples containing natural products. High amounts of pomegranate in the samples led to high weight loss and high phenols and flavonoids delivery. Arnica release seemed to be more difficult than the pomegranate release. All samples presented relative high mechanical properties. In addition, pomegranate samples present higher potential to deliver active compounds than arnica samples. (C) 2017 Wiley Periodicals, Inc.
机译:聚(乙烯醇)(PVA)水凝胶是生物相容性的材料,其在其网络中保留相对大量的含水流体。抗菌天然产物(例如石榴和Arnica)的掺入是一种偶联其杀菌作用的策略,其具有诱饵愈合处理的凝胶的有利性质。这项工作的目标是探讨PVA-石榴和PVA-Arnica样品的微观结构,机械和释放性质。 PVA-石榴样品中的傅里叶变换红外光谱观察到物理相互作用。将石榴与PVA的加入L导出为高T-G,可能与物理相互作用和低T-M和X-C相关,可能是由于PVA链之间的石榴位置。 arnica水平增加与样品x-c的轻微减少有关,可能是由于arnica施加的物理屏障与PVA链的相互作用。 PVA样品呈现比含有天然产物的样品更高的肿胀。样品中的大量石榴导致高量重量损失和高酚类和黄酮类化合物递送。 Arnica释放似乎比石榴释放更困难。所有样品均呈相对高​​机械性能。此外,石榴样品呈现较高的潜力,得到优于Arnica样品的活性化合物。 (c)2017 Wiley期刊,Inc。

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