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首页> 外文期刊>Journal of Molecular Biology >Communicating Genome Architecture: Biovisualization of the Genome, from Data Analysis and Hypothesis Generation to Communication and Learning
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Communicating Genome Architecture: Biovisualization of the Genome, from Data Analysis and Hypothesis Generation to Communication and Learning

机译：沟通基因组结构：基因组的生物化，从数据分析和假设发电到沟通和学习

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摘要

Genome discoveries at the core of biology are made by visual description and exploration of the cell, from microscopic sketches and biochemical mapping to computational analysis and spatial modeling. We outline the experimental and visualization techniques that have been developed recently which capture the three-dimensional interactions regulating how genes are expressed. We detail the challenges faced in integration of the data to portray the components and organization and their dynamic landscape. The goal is more than a single data-driven representation as interactive visualization for de novo research is paramount to decipher insights on genome organization in space.
机译：基因组发现在生物学的核心通过视觉描述和探测细胞，从微观草图和生物化学映射到计算分析和空间建模。 我们概述了最近开发的实验性和可视化技术，该技术捕获了调节基因所表达的三维相互作用。 我们详细介绍了数据集成以描绘组件和组织及其动态景观的挑战。 目标是单个数据驱动的表示，作为De Novo Research的交互式可视化是解码对空间内基因组组织的洞察。

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