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首页> 外文期刊>Biosciences Biotechnology Research Asia >In vitro anti inflammatory activity of methanolic extract of Bacopa monniera by HRBC membrane stabilisation.
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In vitro anti inflammatory activity of methanolic extract of Bacopa monniera by HRBC membrane stabilisation.

机译：HRBC膜稳定作用 Bacopa monniera 的甲醇提取物的体外抗炎活性。

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摘要

Bacopa monniera also referred to as Bacopa monnieri, Herpestis monniera, water hyssop, and "Brahmi," has been used in the Ayurvedic system of medicine for centuries. Phytochemical analysis of B. monniera plant extracts revealed the presence of various biochemical compounds such as alkaloids, flavonoids, glycosides, bacosides, triterpenoids and saponins etc. Since triterpenoids and flavonoids have remarkable anti inflammatory activity, so our present work aims at evaluating the in vitro anti inflammatory activity of B. monniera by HRBC membrane stabilization. The inhibition of hypotonicity induced HRBC membrane lysis was taken as a measure of the anti inflammatory activity. The percentage of membrane stabilisation for methanolic extracts and Diclofenac sodium were done at different concentrations. The maximum percentage of membrane stabilization and hemolysis of B. monniera extracts were found to be 92.92+or-1.41% and 7.08+or-1.17% at a dose of 2000 micro g/ml respectively, when compared to standard Diclofenac sodium was found out to be 98.76+or-1.26% and 1.24+or-0.87% at a dose of 2000 micro g/ml respectively. Therefore, our studies support the isolation and the use of active constituents from B. monniera in treating inflammations.
机译：Bacopa monniera 也称为 Bacopa monnieri ， Herpestis monniera ，水牛膝草和“ Brahmi”，已用于印度草药医学体系中数百年。 B的植物化学分析。 monniera 植物提取物揭示了各种生化化合物的存在，例如生物碱，类黄酮，糖苷，糖苷，三萜类和皂苷等。由于三萜和类黄酮具有显着的抗炎活性，因此我们目前的工作旨在评估体外抗炎活性。 B的炎症活性。膜通过HRBC膜稳定。将低渗诱导的HRBC膜溶解抑制作为抗炎活性的量度。甲醇提取物和双氯芬酸钠的膜稳定百分比在不同浓度下进行。 B的膜稳定和溶血作用的最大百分比。当与标准双氯芬酸钠比较时，发现monniera提取物在2000 micro g / ml剂量下分别为92.92+或-1.41％和7.08+或-1.17％，发现为98.76+或-1.26分别以2000 micro g / ml的剂量分别测定％和1.24+或-0.87％。因此，我们的研究支持从iB中分离和使用活性成分。 monniera 治疗炎症。

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