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首页> 外文期刊>Journal of Physics, D. Applied Physics: A Europhysics Journal >The activation of cancer cells by a nanosecond-pulsed magnetic field generator
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The activation of cancer cells by a nanosecond-pulsed magnetic field generator

机译：纳秒脉冲磁场发生器激活癌细胞

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摘要

Cancer treatment is a challenge in modern medicine. Several novel modalities have been invented to selectively treat cancer cells. The reactive species such as reactive oxygen species and reactive nitrogen species play important role in the anti-cancer capacity of several modalities, such as cold atmospheric plasma. In this study, we first demonstrated that a nanosecond-pulsed magnetic field (NMF) generator could sensitize the melanoma cell line B16-F10 to the cytotoxicity of an important ROS, H2O2. The magnetic field strength and the frequency were two key factors to control the activation level of NMF treatment. This study provided a novel strategy to use electromagnetic modality in cancer treatment particularly for the treatment on deep tumors such as brain, pancreatic, etc.
机译：癌症治疗是现代医学中的挑战。 已经发明了几种新型方式以选择性地治疗癌细胞。 反应性氧物质和反应性氮物质如反应性物质在抗癌能力中起重要作用，例如冷大气等离子体。 在这项研究中，我们首先证明纳秒脉冲磁场（NMF）发生器可以使黑素瘤细胞系B16-F10敏感到重要ROS，H2O2的细胞毒性。 磁场强度和频率是控制NMF处理的激活水平的两个关键因素。 本研究提供了一种新颖的策略，用于使用癌症治疗中的电磁体模式，特别是对脑，胰腺等深肿瘤的治疗

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