...
  • 主题
高级搜索  >
历史搜索 清空历史
首页> 外文期刊>Journal of the American Geriatrics Society >Inhaler Technique Education and Exacerbation Risk in Older Adults with Asthma or Chronic Obstructive Pulmonary Disease: A Meta-Analysis
【24h】

Inhaler Technique Education and Exacerbation Risk in Older Adults with Asthma or Chronic Obstructive Pulmonary Disease: A Meta-Analysis

机译：哮喘或慢性阻塞性肺病的老年人的吸入器技术教育和加剧风险：Meta分析

获取原文
获取原文并翻译 | 示例
           
页面导航
  • 摘要
  • 著录项
  • 相似文献
  • 相关主题

摘要

Objectives To evaluate the effect of inhaler education programs on clinical outcomes and exacerbation rates in older adults with asthma or chronic obstructive pulmonary disease (COPD). Design Systematic review and meta-analysis. Setting and Participants Older adults with asthma or COPD, either in primary or secondary health care and pharmacy setting. Measurements We searched the Medline, Embase, and Central databases according to the main eligibility criteria for inclusion: systematic reviews, meta-analysis, clinical trials and quasi-experimental studies; participants aged 65 and older; education on inhaler technique and reporting of disease control and exacerbation rates. We used the Grading of Recommendations, Assessment, Development and Evaluations scale for quality assessment and used a random-effect model with Mantel-Haenszel adjustment to perform a meta-analysis. Results We included 8 studies (4 randomized, 4 quasi-experimental) with a total of 1,812 participants. The most frequent type of intervention was physical demonstration of inhaler technique, training with placebo devices. Five studies showed significant reduction in exacerbation rates (pooled risk ratio=0.71, 95% confidence interval=0.59-0.86; p .001), although effect on disease control and quality of life showed high discrepancy in the reported results, and all randomized studies revealed uncertainty in their risk of bias assessment. Conclusion All interventions seemed to improve inhaler performance and clinically relevant outcomes, but a placebo device could be the most effective. There is evidence that interventions reduce exacerbation risk in older adults, although to an overall moderate degree. J Am Geriatr Soc 67:57-66, 2019.
机译：目的评估的吸入教育计划对临床结果和恶化率在老年人患有哮喘或慢性阻塞性肺疾病（COPD）的影响。设计系统评价和荟萃分析。制定和哮喘或慢性阻塞性肺病的与会者老年人，无论是在一级或二级医疗保健和药房环境。测量我们检索了MEDLINE，EMBASE，和中央数据库，根据纳入的主要资格条件：系统评价，荟萃分析，临床试验和准实验研究; 65岁及以上的参与者;教育对吸入器技术和疾病控制和恶化率的报告。我们使用建议的分级，评估，开发和评估量表质量评估和使用曼特尔 - 亨塞尔调整的随机效应模型进行荟萃分析。结果共纳入8个研究（4随机，4类实验），共有1,812人参加。最常见的类型的干预是吸入器技术的物理演示，与安慰剂设备训练。五个研究表明在恶化率显著减少（合并风险比= 0.71，95％置信区间= 0.59-0.86; P＆LT; 0.001），尽管对疾病控制和生活质量的影响在所报告的结果表明高差异，并且所有随机研究中他们的偏见评估风险揭示不确定性。结论所有的干预似乎改善吸入器的性能和临床相关的结果，但安慰剂设备可能是最有效的。有证据表明，干预减少老年人恶化的风险，虽然总体适度。 Ĵ上午Geriatr志67：57-66，2019。

著录项

相似文献

  • 外文文献
  • 中文文献
  • 专利
获取原文

客服邮箱：kefu@zhangqiaokeyan.com

京公网安备：11010802029741号 ICP备案号：京ICP备15016152号-6 六维联合信息科技 (北京) 有限公司©版权所有

  • 客服微信

  • 服务号