...
  • 主题
高级搜索  >
历史搜索 清空历史
首页> 外文期刊>COPD: Journal of Chronic Obstructive Pulmonary Disease >An Estimate of the Prevalence of COPD in Africa: A Systematic Analysis
【24h】

An Estimate of the Prevalence of COPD in Africa: A Systematic Analysis

机译：非洲COPD患病率估算：系统分析

获取原文
获取原文并翻译 | 示例
   

获取外文期刊封面封底 >>

       
页面导航
  • 摘要
  • 著录项
  • 相似文献
  • 相关主题

摘要

Background: Chronic obstructive pulmonary disease (COPD) is among the leading causes of death globally, accounting for about 3 million deaths worldwide in 2011. We aimed to estimate the prevalence of COPD in Africa in the year 2010 to provide the information that could assist health policy in the region. Methods: We conducted a systematic review of Medline, EMBASE and Global Health for studies on COPD published between 1990 and 2012. We included original population based studies providing estimates of the prevalence of COPD. We considered the reported estimates in terms of the mean age of the sample, sex ratio, the year of study and the country of the study as possible covariates. Results from two different types of studies, i.e., based on spirometric and non-spirometric diagnosis of COPD, were further compared. The United Nation Population Division's population figures were used to estimate the number of COPD cases in the year 2010. Results: Our search returned 243 studies, from which only 13 met our selection criteria and only five were based on spirometry. The difference in the median prevalence of COPD in persons aged 40 years or older based on spirometry data (13.4%; IQR: 9.4%-22.1%) and non-spirometry data (4.0%; IQR: 2.1%-8.9%) was statistically significant (p = 0.001). There was no significant effect of the gender or the year of the study on the reported prevalence of COPD in either set of studies. The prevalence of COPD increased with age in spirometry-based studies (p = 0.017), which is a plausible finding suggesting internal consistency of spirometry-based estimates, while this trend was not observed in studies using other case definitions. When applied to the appropriate age group (40 years or more), which accounted for 196.4 million people in Africa in 2010, the estimated prevalence translates into 26.3 million (18.5-43.4 million) cases of COPD. Comparable figures for the year 2000 based on the same prevalence rates would amount to 20.0 million (14.1-33.1), suggesting an increase of 31.5% over a decade that is attributable to ageing of the African population alone. Conclusion: Our findings suggest that COPD is likely to already represent a very large public health problem in Africa. Moreover, rapidly ageing African population should expect a steady increase in the number of COPD cases in the next decade and beyond. The quantity and quality of available evidence does not match the size of the problem. There is a need for more research on COPD prevalence, but also incidence, mortality and risk factors in Africa. We hope this study will raise awareness of COPD in Africa and encourage further research.
机译：背景：慢性阻塞性肺疾病（COPD）是全球主要的死亡原因之一，2011年占全球死亡人数约300万人。我们旨在估计2010年非洲COPD的患病率，以提供有助于健康的信息该地区的政策。方法：我们对1990年至2012年间发表的关于COPD的研究进行了Medline，EMBASE和Global Health的系统评价。我们纳入了基于人群的原始研究，以估计COPD的患病率。我们认为，根据样本的平均年龄，性别比，研究年份和研究国家/地区来报告的估算值可能是协变量。进一步比较了两种不同类型研究的结果，即基于对COPD的肺功能测定和非肺功能测定的诊断。联合国人口司的人口数据用于估计2010年的COPD病例数。结果：我们的搜索返回了243项研究，其中只有13项符合我们的选择标准，只有5项基于肺活量测定法。根据肺活量测定数据（13.4％; IQR：9.4％-22.1％）和非肺活量测定数据（4.0％; IQR：2.1％-8.9％），年龄在40岁或40岁以上人群中COPD患病率中位数的差异具有统计学意义显着性（p = 0.001）。在两组研究中，性别或研究年份对报告的COPD患病率均无显着影响。在基于肺活量测定的研究中，COPD的患病率随年龄增加而增加（p = 0.017），这是一个合理的发现，表明基于肺活量测定的估计值具有内部一致性，而在使用其他病例定义的研究中未观察到这种趋势。如果将其应用于适当的年龄段（40岁以上），该年龄段在2010年占非洲的1.964亿人口，则估计的流行率将转化为2630万（1850-4340万）COPD病例。根据相同的患病率，2000年的可比数字将达到20.0百万（14.1-33.1），这表明十年来增长了31.5％，这可归因于非洲人口的老龄化。结论：我们的发现表明，COPD可能已经代表了非洲非常大的公共卫生问题。此外，迅速老龄化的非洲人口应期望在未来十年及以后的期间内，COPD病例数将稳定增长。现有证据的数量和质量与问题的规模不符。需要对非洲的COPD患病率，发病率，死亡率和危险因素进行更多的研究。我们希望这项研究能够提高非洲对COPD的认识，并鼓励进一步的研究。

著录项

相似文献

  • 外文文献
  • 中文文献
  • 专利
获取原文

客服邮箱：kefu@zhangqiaokeyan.com

京公网安备：11010802029741号 ICP备案号：京ICP备15016152号-6 六维联合信息科技 (北京) 有限公司©版权所有

  • 客服微信

  • 服务号