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Comparison of pentazocine and fentanyl in total intravenous anesthesia using propofol

机译：异丙醇总静脉内麻醉中芬芳和芬太尼的比较

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BACKGROUND: Pentazocine may be an alternative for fentanyl during total intravenous anesthesia (TIVA) using propofol. The authors compared the efficacy and safety of pentazocine for analgesics in TIVA using propofol. METHODS: Eighty-nine patients scheduled for mastectomy were analyzed retrospectively. Patients were classified into two groups by used analgesics; pentazocine (Group P, n = 34) and fentanyl (Group F, n = 55). Anesthesia was induced with propofol, using target controlled infusion method, and ketamine 20-50 mg, and was maintained with propofol infusion and increments of fentanyl or single dose of pentazocine with 40% oxygen in air. Postoperative pain was assessed using a visual analogue pain scale (VAS). RESULTS: There were no differences in the patient background between both groups. Systolic as well as diastolic blood pressure and heart rate were not different between both groups during surgery. The maintenance dose of propofol was not different between the two groups. Awakening time in about 80% of patients was within 15 minutes and is not different between the two groups. There were no differences between the two groups regarding VAS. There are no severe complications. Incidence of nausea and vomiting was not different between the two groups. CONCLUSIONS: The results suggest that pentazocine would provide a stable hemodynamic state, rapid recovery and an effective postoperative pain relief to the same degree as with fentanyl in TIVA with propofol.
机译：背景：在使用异丙酚的总静脉内麻醉（TIVA）期间，所述泽蓟犬可以是芬太尼的替代品。作者比较了使用异丙酚在TIVA中镇痛药的疗效和安全性的疗效和安全性。方法：回顾性分析乳房切除术的八十九名患者。患者通过二手镇痛药分为两组;使杂志杂志（P组，n = 34）和芬太尼（F组，n = 55）。使用靶控制输注方法和氯胺酮诱导麻醉，并用氯胺酮输注和芬太尼的芬太尼（单剂量的戊胺，所述戊胺，所述戊二籽或单剂量在所述空气中保持40％氧气。使用视觉模拟疼痛量表（VAS）评估术后疼痛。结果：两组之间的患者背景没有差异。在手术期间，两个组之间的收缩系统以及舒张压和心率不差异。双基团的维持剂量在两组之间不具有不同。大约80％的患者在15分钟内唤醒时间在两组之间不存在。关于VAS的两组之间没有差异。没有严重的并发症。两组之间恶心和呕吐的发病率并不不同。结论：结果表明，五泽鸟类将提供稳定的血液动力学状态，快速恢复和有效的术后疼痛缓解与富苯基用异丙酚中的芬太尼的程度相同。

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