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首页> 外文期刊>Academic radiology >3D Assessment of Lymph Nodes vs. RECIST 1.1.
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3D Assessment of Lymph Nodes vs. RECIST 1.1.

机译：淋巴结的3D评估与RECIST 1.1。

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摘要

RATIONALE AND OBJECTIVES: In today's clinical practice, the size of lymph nodes is assessed by measuring the long and the short axis in the axial plane. This study compares this approach with three-dimensional (3D) assessment. MATERIALS AND METHODS: For a representative set of 49 lymph nodes, the axes in the axial plane have been measured and a 3D model has been created manually. Based on the 3D model, the real axial long and short axis as well as the three 3D axes and the volume have been computed and compared to the measured axial axes. RESULTS: The inter-observer variability is around 10% for all measured lengths and almost 16% for the computed volume. The average relative error of the measured long (short) axial axis is 9.73% (24.57%) to the computed axial axis and 25.05% (19.97%) to the computed 3D axis, respectively. The product of the axial long axis and the square of the axial short axis provides best correlation to the volume. CONCLUSION: This study confirms Response Evaluation Criteria In Solid Tumours 1.1 that measuring the short axis is more robust than measuring the long axis because of less impact of the node's spatial orientation. Nonetheless it is shown that considering both axes is a better prognostic factor for the volume than measuring the short axis only.
机译：理由和目的：在当今的临床实践中，淋巴结的大小是通过测量轴向平面中的长轴和短轴来评估的。这项研究将该方法与三维（3D）评估进行了比较。材料和方法：对于一组代表性的49个淋巴结，测量了轴平面中的轴，并手动创建了3D模型。基于3D模型，已计算出实际的长轴和短轴以及三个3D轴和体积，并将其与测量的轴进行比较。结果：所有测量长度的观察者间差异约为10％，计算体积的差异约为16％。测量的长（短）轴的平均相对误差相对于计算出的轴向轴为9.73％（24.57％），而相对于计算出的3D轴则为25.05％（19.97％）。轴向长轴与轴向短轴的平方的乘积提供了与体积的最佳相关性。结论：这项研究证实了实体瘤1.1中的反应评估标准，因为节点的空间取向的影响较小，所以测量短轴比测量长轴更可靠。尽管如此，已经表明，与仅测量短轴相比，考虑到两个轴是更好的预后因素。

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