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首页> 外文期刊>Academic radiology >Dose Reduction Does Not Affect Detection of Bone Marrow Lesions with Dual-energy CT Virtual Noncalcium Technique
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Dose Reduction Does Not Affect Detection of Bone Marrow Lesions with Dual-energy CT Virtual Noncalcium Technique

机译：双能量CT虚拟非钙技术降低剂量不会影响对骨髓病变的检测

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摘要

Rationale and Objectives: The aim of this study was to evaluate if a dose-reduced, dose-neutral dual-energy computed tomographic (CT) virtual noncalcium technique can equally detect posttraumatic bone marrow lesions (BMLs) of the knee. Materials and Methods: Fifty patients underwent DE CT imaging with either a standard dose (group A) or a dose equal to that of a single-energy CT scan (group B) (28% dose reduction) and magnetic resonance imaging for knee trauma workup. Calcium was virtually subtracted from the images. Two radiologists rated the presence of abnormal soft tissue-like attenuation in the bone marrow in a total of 12 femoral and tibial regions and performed Hounsfield unit measurements thereafter. Receiver-operating characteristic curve analysis was used for four-point rating scores and Hounsfield unit measurements. Fractures were classified. Results: Magnetic resonance imaging depicted 170 BMLs (35 femoral, 135 tibial). Mean age, number of fractures, attenuation values and number of regions with BMLs were not significantly different between the groups. Visual rating revealed overall areas under the curves of 0.983 and 0.979 for observers 1 and 2, respectively. Visual judgment was superior to attenuation measurements for femoral regions regardless of the dose applied. Analysis of variance of all CT values revealed a significant influence for the presence of edema (P < 001) but no differences for the radiation dose used (P = 424). Interobserver agreement was excellent (κ = 0.944). Conclusions: Dose reduction does not affect the detectability of posttraumatic BMLs with a dual-energy CT virtual noncalcium technique, thereby providing potential additional information compared with single-energy CT imaging without additional radiation dose.
机译：原理和目的：这项研究的目的是评估减少剂量，剂量中性的双能计算机断层扫描（CT）虚拟非钙技术是否可以同样地检测膝关节创伤后骨髓损伤（BML）。材料和方法：50例患者接受了标准剂量（A组）或等于单能CT扫描剂量（B组）（剂量降低28％）的DE CT成像，并进行了磁共振成像以检查膝关节创伤。实际上从图像中减去了钙。两名放射科医生对总共12个股骨和胫骨区域中骨髓中异常软组织样衰减的存在进行了评估，然后对其进行了Hounsfield单位测量。接收机操作特性曲线分析用于四点评分和Hounsfield单位测量。骨折被分类。结果：磁共振成像显示170 BML（股骨35例，胫骨135例）。两组之间的平均年龄，骨折数量，衰减值和BML区域数量没有显着差异。视觉评级显示观察者1和观察者2分别在0.983和0.979曲线下的总面积。无论使用何种剂量，视觉判断均优于股骨区域衰减测量。所有CT值的方差分析表明，对水肿的存在有显着影响（P <001），但所用放射剂量没有差异（P = 424）。观察者之间的一致性非常好（κ= 0.944）。结论：减少剂量不会影响采用双能CT虚拟非钙技术的创伤后BML的可检测性，从而与没有额外辐射剂量的单能CT成像相比可提供潜在的附加信息。

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