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Three-dimensional magnetic resonance imaging using single breath-hold k-t BLAST for assessment of global left ventricular functional parameters

机译:使用一次屏气k-t BLAST进行三维磁共振成像以评估整体左心室功能参数

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Objectives: To determine the accuracy of three-dimensional k-t broad-use linear acquisition speed-up technique (k-t BLAST) accelerated magnetic resonance imaging (MRI) for the assessment of left ventricular (LV) parameters compared to segmented multiple breath-hold cine imaging. Methods: A multislice cine (steady state free precession [SSFP]) sequence was performed with complete ventricular coverage during multiple breath-holds (temporal resolution 47ms, voxel size 1.25 × 1.25×8 mm3). In addition, two k-t BLAST sequences with complete coverage were acquired, KT1 (temporal resolution 57ms, voxel size 1.25 × 1.25×4 mm3) and k-t2 (temporal resolution 57ms, voxel size 1.25 × 1.25×8 mm3), during a single breath-hold. For comparison of SSFP and k-t BLAST, LV parameters were determined: ejection fraction (EF), end-diastolic volume, end-systolic volume, and LV mass. Results: EF was underestimated by KT1 (47%) and KT2 (48%) compared to the SSFP sequence (53%). All parameters showed high correlation with the k-t BLAST sequences and the SSFP sequence (r=0.88-0.98, P .001). The mean relative difference for KT1/KT2 compared to the SSFP sequence was -0.11/-0.09 for the EF, -0.073/-0.086 for the EDV, 0.044/0.051 for the ESV, and 0.085/0.12 for the LV mass. Conclusions: The use of three-dimensional k-t BLAST enabled a determination of the LV parameters with high correlation compared to the SSFP sequence. EF was slightly underestimated, and LV mass was slightly overestimated.
机译:目的:确定与分段多屏气电影成像相比,三维kt广泛使用线性采集加速技术(kt BLAST)加速磁共振成像(MRI)评估左心室(LV)参数的准确性。方法:在多次屏气期间(时间分辨率为47ms,体素大小为1.25×1.25×8 mm3),进行了多层电影(无稳态进动[SSFP])序列的完整心室覆盖。此外,在一次采集中获得了两个完全覆盖的kt BLAST序列,即KT1(时间分辨率57ms,体素大小1.25×1.25×4 mm3)和k-t2(时间分辨率57ms,体素大小1.25×1.25×8 mm3)。屏住呼吸。为了比较SSFP和k-t BLAST,确定了LV参数:射血分数(EF),舒张末期容积,收缩末期容积和LV质量。结果:与SSFP序列(53%)相比,KT1(47%)和KT2(48%)低估了EF。所有参数均显示与k-t BLAST序列和SSFP序列高度相关(r = 0.88-0.98,P <.001)。与SSFP序列相比,KT1 / KT2的平均相对差值对于EF为-0.11 / -0.09,对于EDV为-0.073 / -0.086,对于ESV为0.044 / 0.051,对于LV质量为0.085 / 0.12。结论:与SSFP序列相比,三维k-t BLAST的使用可以确定高度相关的LV参数。 EF被低估了,LV质量被高估了。

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