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首页> 外文期刊>Academic radiology >Low-dose unenhanced CT for IV contrast bolus timing: is it reliable to assess hepatic steatosis?
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Low-dose unenhanced CT for IV contrast bolus timing: is it reliable to assess hepatic steatosis?

机译：低剂量CT静脉造影剂增强时未增强：评估肝脂肪变性是否可靠？

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RATIONALE AND OBJECTIVES: To determine whether an unenhanced low-dose image acquired during automated contrast bolus timing can be used to assess hepatic steatosis. MATERIALS AND METHODS: Fifty subjects (29 male, 21 female; 26-92 years; mean body mass index (BMI; 26.9) with abdominal multiphasic computed tomography were included. Abdominal diameters and circumferences were derived from anteroposterior and lateral scout radiographs. Hepatic attenuation (HA) was measured on unenhanced low-dose images (120 kV; 40 mA; 0.5 seconds' rotation time) and corresponding unenhanced standard-dose images (120 kV, z-axis automatic tube current modulation, noise index 11.5). Noise estimates were measured in surrounding air. Pearson correlation was calculated between abdominal circumference and BMI. Mean HA assessed on low-dose images and standard-dose images was compared using a paired Student's t-test and Bland Altman plots. RESULTS: Abdominal circumference (mean, 142.8cm) correlated well with BMI (r = 0.83). No significant difference was found for HA on low-dose images (mean +57.7 HU) compared to HA on standard-dose images (+56.0 HU) (P = .077). Image noise (+11.5 HU) was significantly higher on low-dose images compared to image noise (+8.1 HU) on standard-dose images (P < .05). For HA mean difference comparing low- and standard-dose images was -1.7 HU (limits of agreement: -14.6, 11.2). CONCLUSION: In all subjects, hepatic attenuation can be correctly assessed on unenhanced low-dose images.
机译：理由和目的：要确定在自动对比推注定时中获得的未增强的低剂量图像是否可用于评估肝脂肪变性。材料与方法：包括五十名受试者（男29例，女21例; 26-92岁;平均体重指数（BMI）; 26.9），并进行腹部多相X线断层扫描;腹部直径和周长来自前后位和侧向X线片摄片。 （HA）是在未增强的低剂量图像（120 kV; 40 mA; 0.5秒的旋转时间）和相应的未增强的标准剂量图像（120 kV，z轴自动管电流调制，噪声指数11.5）下测量的。在周围空气中进行测量，计算腹围与BMI之间的皮尔逊相关性，使用成对的Student t检验和Bland Altman图对低剂量图像和标准剂量图像上评估的平均HA进行比较。 142.8cm）与BMI相关性很好（r = 0.83）。与标准剂量图像（+56.0 HU）的HA相比，低剂量图像（平均+57.7 HU）的HA没有发现显着差异（P = .077） 。影像杂讯（+1与标准剂量图像上的图像噪声（+8.1 HU）相比，低剂量图像上的1.5 HU）明显更高（P <.05）。对于HA，比较低剂量和标准剂量图像的平均差异为-1.7 HU（一致度：-14.6，11.2）。结论：在所有受试者中，可以在未增强的低剂量图像上正确评估肝衰减。

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