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首页> 外文期刊>Academic radiology >Non-contrast enhanced MRI for evaluation of breast lesions: comparison of non-contrast enhanced high spectral and spatial resolution (HiSS) images versus contrast enhanced fat-suppressed images.
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Non-contrast enhanced MRI for evaluation of breast lesions: comparison of non-contrast enhanced high spectral and spatial resolution (HiSS) images versus contrast enhanced fat-suppressed images.

机译：非对比增强MRI用于评估乳腺病变：对比非对比增强的高光谱和空间分辨率（HiSS）图像与对比增强脂肪抑制的图像。

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RATIONALE AND OBJECTIVES: The aims of this study were to evaluate high spectral and spatial resolution (HiSS) magnetic resonance imaging (MRI) for the diagnosis of breast cancer without the injection of contrast media by comparing the performance of precontrast HiSS images to that of conventional contrast-enhanced, fat-suppressed, T1-weighted images on the basis of image quality and in the task of classifying benign and malignant breast lesions. MATERIALS AND METHODS: Ten benign and 44 malignant lesions were imaged at 1.5 T with HiSS (precontrast administration) and conventional fat-suppressed imaging (3-10 minutes after contrast administration). This set of 108 images, after randomization, was evaluated by three experienced radiologists blinded to the imaging technique. Breast Imaging Reporting and Data System morphologic criteria (lesion shape, lesion margin, and internal signal intensity pattern) and final assessment were used to measure reader performance. Image quality was evaluated on the basis of boundary delineation and quality of fat suppression. An overall probability of malignancy was assigned to each lesion for HiSS and conventional images separately. RESULTS: On boundary delineation and quality of fat suppression, precontrast HiSS scored similarly to conventional postcontrast MRI. On benign versus malignant lesion separation, there was no statistically significant difference in receiver-operating characteristic performance between HiSS and conventional MRI, and HiSS met a reasonable noninferiority condition. CONCLUSIONS: Precontrast HiSS imaging is a promising approach for showing lesion morphology without blooming and other artifacts caused by contrast agents. HiSS images could be used to guide subsequent dynamic contrast-enhanced MRI scans to maximize spatial and temporal resolution in suspicious regions. HiSS MRI without contrast agent injection may be particularly important for patients at risk for contrast-induced nephrogenic systemic fibrosis or allergic reactions.
机译：理由和目的：本研究的目的是通过对比造影剂HiSS图像与常规造影剂的性能，评估无需注射造影剂的高光谱和空间分辨率（HiSS）磁共振成像（MRI）来诊断乳腺癌。在图像质量的基础上，以及在对良性和恶性乳腺病变进行分类的任务中，使用对比度增强，脂肪抑制的T1加权图像。材料与方法：用HiSS（造影剂预给药）和常规的脂肪抑制成像（造影剂给药后3-10分钟）在1.5 T下对10个良性和44个恶性病变进行成像。这组108张图像在随机化后由三位对成像技术不了解的经验丰富的放射科医生进行了评估。乳房成像报告和数据系统形态学标准（病变形状，病变边缘和内部信号强度模式）和最终评估被用来测量阅读器性能。根据边界轮廓和抑制脂肪的质量评估图像质量。对于HiSS和常规图像，分别将每个肿瘤的恶性总概率分配给患者。结果：在边界描绘和脂肪抑制的质量上，造影剂HiSS的评分与常规造影剂MRI相似。在良性与恶性病变分离方面，HiSS与常规MRI在接收者操作特征方面没有统计学上的显着差异，并且HiSS符合合理的非劣性条件。结论：造影前HiSS成像是一种有前景的方法，可显示病变形态，而不会出现由造影剂引起的起霜和其他伪影。 HiSS图像可用于指导后续的动态对比增强MRI扫描，以在可疑区域中最大化空间和时间分辨率。对于没有造影剂肾病性全身纤维化或过敏反应风险的患者，未注射造影剂的HiSS MRI可能尤其重要。

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