Focused ultrasound is capable of delivering energy into tissue, non-invasively and without the use of ionizing radiation.~1 The ability of focused ultrasound to generate heat in tissue was demonstrated in the brain decades ago, with the creation of lesions in the mammalian central nervous system.~2 A spherically focused ultrasonic transducer causes emitted ultrasound waves to superimpose constructively at a focus, leading to very high energy deposition within a small volume, of a size proportional to the wavelength. Focused ultrasound is an emerging non-invasive alternative to surgery and an alternative to radiation therapy. This has led to the use of ultrasound in non-invasive hyperthermia and ablative applications, such as the treatment of uterine fibroids.~3
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