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首页> 外文期刊>Acta Cardiologica >Infections of implantable cardiac rhythm devices: Predisposing factors and outcome
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Infections of implantable cardiac rhythm devices: Predisposing factors and outcome

机译：植入式心律装置的感染：诱发因素和结果

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Background and objective Infection is a serious complication of cardiac devices. We aimed to describe predisposing factors and outcome of permanent pacemaker (PPM) and implantable cardioverter/defibrillator (ICD) infections. Method We reviewed cardiac device infections diagnosed at the Yuksek Ihtisas Hospital Ankara, Turkey, between 2004 and 2010 retrospectively. Demographic and clinical data were collected, descriptive analysis was performed. Results From 2004 to 2010, a total of 1916 devices were implanted. Thirty-four cases of confirmed device infections were identified giving an infection rate of 1.7%. Seventy-three percent of the cases were men. Mean age was 58 ± 19 years. Twenty-two patients had a PPM, 12 had an ICD or cardiac resynchronization therapy (CRT). Diabetes mellitus, hypertension, cardiac failure, anaemia and immune suppression were prominent comorbidities. Previously, 6 (17%) patients had a history of replacement, 6 (17%) had revision, 3 (8%) had haematoma. Ten (29%) patients reported a history of long hospital stay and 13 (38%) patients had multiple hospitalizations. Pocket infection (70%) was the most common clinical presentation. Ninety-one percent of patients were cured with both device removal and antibiotic administration. Complications of cardiac device infections included septic emboli, acute renal failure, inotropic infusion requirement which were mostly seen among patients with endocarditis. Five patients suffered relapsing infection. Three patients died, among them two had infective endocarditis. Conclusion Cardiac device infections have been encountered more often in recent years. Cure of device infections is achievable in a majority of patients treated with antimicrobial treatment and complete device removal although device-related endocarditis can have an aggressive course.
机译：背景和目的感染是心脏设备的严重并发症。我们旨在描述永久性起搏器（PPM）和植入式心脏复律器/除颤器（ICD）感染的诱因和结局。方法我们回顾性分析了2004年至2010年之间在土耳其安卡拉的Yuksek Ihtisas医院诊断出的心脏设备感染情况。收集人口统计学和临床​​数据，进行描述性分析。结果2004年至2010年，共植入了1916台设备。确认了34例确诊的器械感染病例，感染率为1.7％。 73％的病例是男性。平均年龄为58±19岁。 22名患者有PPM，12名患者进行了ICD或心脏再同步治疗（CRT）。糖尿病，高血压，心力衰竭，贫血和免疫抑制是突出的合并症。以前，有6名（17％）患者有置换史，有6名（17％）曾有翻修史，有3名（8％）有血肿。 10名（29％）患者报告有长期住院历史，而13名（38％）患者曾多次住院。口袋感染（70％）是最常见的临床表现。百分之九十一的患者在去除器械和抗生素后治愈。心脏设备感染的并发症包括败血性栓子，急性肾功能衰竭，需要进行变力性输液，这些多见于心内膜炎患者。五例患者复发感染。 3例患者死亡，其中2例感染性心内膜炎。结论近年来，心脏器械感染的发生率更高。尽管与器械有关的心内膜炎可能具有侵袭性病程，但在大多数接受抗菌治疗并彻底清除器械的患者中，可以治愈器械感染。

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