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首页> 外文期刊>Acta biomaterialia >Selective laser sintering of hydroxyapatite/poly-epsilon-caprolactone scaffolds.
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Selective laser sintering of hydroxyapatite/poly-epsilon-caprolactone scaffolds.

机译：羟基磷灰石/聚ε-己内酯支架的选择性激光烧结。

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摘要

Selective laser sintering (SLS) enables the fabrication of complex geometries with the intricate and controllable internal architecture required in the field of tissue engineering. In this study hydroxyapatite and poly-epsilon-caprolactone, considered suitable for hard tissue engineering purposes, were used in a weight ratio of 30:70. The quality of the fabricated parts is influenced by various process parameters. Among them Four parameters, namely laser fill power, outline laser power, scan spacing and part orientation, were identified as important. These parameters were investigated according to a central composite design and a model of the effects of these parameters on the accuracy and mechanical properties of the fabricated parts was developed. The dimensions of the fabricated parts were strongly dependent on the manufacturing direction and scan spacing. Repeatability analysis shows that the fabricated features can be well reproduced. However, there were deviations from the nominal dimensions, with the features being larger than those designed. The compressive modulus and yield strength of the fabricated microstructures with a designed relative density of 0.33 varied between 0.6 and 2.3 and 0.1 and 0.6 MPa, respectively. The mechanical behavior was strongly dependent on the manufacturing direction.
机译：选择性激光烧结（SLS）能够制造复杂的几何形状，并具有组织工程领域所需的复杂且可控的内部结构。在这项研究中，羟基磷灰石和聚ε-己内酯被认为适用于硬组织工程目的，其重量比为30:70。所制造零件的质量受各种工艺参数的影响。其中四个参数，即激光填充功率，轮廓激光功率，扫描间距和零件方向被确定为重要参数。根据中心复合设计对这些参数进行了研究，并开发了这些参数对所制造零件的精度和机械性能的影响的模型。所制造零件的尺寸在很大程度上取决于制造方向和扫描间距。重复性分析表明，制作的特征可以很好地复制。但是，与公称尺寸存在偏差，其特征大于设计的特征。设计的相对密度为0.33的微结构的压缩模量和屈服强度分别在0.6和2.3之间以及0.1和0.6 MPa之间变化。机械性能在很大程度上取决于制造方向。

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