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Bismuth-doped injectable calcium phosphate cement with improved radiopacity and potent antimicrobial activity for root canal filling.

机译:铋掺杂的可注射磷酸钙水泥,具有增强的不透射线性和对根管充填的有效抗菌活性。

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摘要

A bismuth-doped injectable calcium phosphate cement (BD-ICPC) with improved radiopacity, potent antimicrobial activity and sealability was developed by introducing bismuth salicylate basic (BSB) into the powder phase of the calcium phosphate cement (CPC). The results showed that the radiopacity and sealability of BD-ICPC were improved compared with pure ICPC. Although BSB had a retarding effect on the setting rate of the cement, the addition of BSB reduced the viscosity and yield stress of BD-ICPC, thus enhanced its injectability. It was noteworthy that BD-ICPC had a potent antimicrobial activity with improved sealability. In addition, BD-ICPC afforded a uniform and tight adaptation to the root canal wall. These results indicate that BD-ICPC possesses a combination of good in vitro radiopacity, high injectability, potent antimicrobial activity, improved sealability and tight adaptation to the root canal. It is expected to be used as a novel root canal filling material.
机译:通过将水杨酸铋碱(BSB)引入磷酸钙水泥(CPC)的粉末相中,开发出具有改善的射线不透性,有效的抗菌活性和密封性的掺铋可注射磷酸钙水泥(BD-ICPC)。结果表明,与纯ICPC相比,BD-ICPC的射线不透性和密封性得到了改善。尽管BSB对水泥的固化速率有延迟作用,但是BSB的加入降低了BD-ICPC的粘度和屈服应力,从而增强了其可注入性。值得注意的是,BD-ICPC具有强大的抗菌活性,并具有改善的密封性。此外,BD-ICPC提供了对根管壁的均匀而紧密的适应。这些结果表明,BD-ICPC具有良好的体外不透射线性,高注射性,有效的抗菌活性,改善的密封性和对根管的紧密适应性。有望用作新型的根管充填材料。

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