The role of surface wettability and surface charge of electrosprayed nanoapatites on the behaviour of osteoblasts.

Thian ES; Ahmad Z; Huang J; Edirisinghe MJ; Jayasinghe SN; Ireland DC; Brooks RA; Rushton N; Bonfield W; Best SM

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The role of surface wettability and surface charge of electrosprayed nanoapatites on the behaviour of osteoblasts.

机译：电喷涂纳米磷灰石的表面润湿性和表面电荷对成骨细胞行为的作用。

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A new deposition method is presented, based on electrospraying, that can build bioceramic structures with desirable surface properties. This technology allows nanoapatite crystals, including hydroxyapatite (nHA), carbonate-substituted HA (nCHA) and silicon-substituted HA (nSiHA), to be electrosprayed on glass substrates. Human osteoblast cells cultured on nSiHA showed enhanced cell attachment, proliferation and protein expression, namely alkaline phosphatase, type 1 collagen and osteocalcin, as compared to nHA and nCHA. The modification of nanoapatite by the addition of silicon into the HA lattice structure renders the electrosprayed surface more hydrophilic and electronegatively charged.

机译：提出了一种基于电喷雾的新沉积方法，该方法可以构建具有所需表面特性的生物陶瓷结构。该技术允许将纳米羟基磷灰石晶体（包括羟基磷灰石（nHA），碳酸盐取代的HA（nCHA）和硅取代的HA（nSiHA））电喷涂在玻璃基板上。与nHA和nCHA相比，在nSiHA上培养的人类成骨细胞显示出增强的细胞附着，增殖和蛋白质表达，即碱性磷酸酶，1型胶原和骨钙素。通过将硅添加到HA晶格结构中来改性纳米磷灰石，使电喷涂表面更亲水和带负电。

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《Acta biomaterialia》 |2010年第3期|共6页
作者
Thian ES; Ahmad Z; Huang J; Edirisinghe MJ; Jayasinghe SN; Ireland DC; Brooks RA; Rushton N; Bonfield W; Best SM;
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1. The role of surface wettability and surface charge of electrosprayed nanoapatites on the behaviour of osteoblasts. [J] . Thian ES, Ahmad Z, Huang J, Acta biomaterialia . 2010,第3期

机译：电喷涂纳米磷灰石的表面润湿性和表面电荷对成骨细胞行为的作用。
2. Electrokinetics over charge-modulated surfaces in the presence of patterned wettability: Role of the anisotropic streaming potential [J] . Uddipta Ghosh, Suman Chakraborty PHYSICAL REVIEW E . 2013,第3期

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3. Surface wettability of montmorillonite (001) surface as affected by surface charge and exchangeable cations: A molecular dynamic study [J] . Yi Hao, Jia Feifei, Zhao Yunliang, Applied Surface Science . 2018,第NOVa30期

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4. Interface state densities and surface charge on wet-chemically prepared Si(100) surfaces [C] . H. Angermann, RENA, FSI International, International Symposium on Ultra Clean Processing of Silicon Surfaces . 2005

机译：湿化化学制备的Si（100）表面上的界面状态密度和表面电荷
5. Electro-thermally polarized bulk and coated hydroxyapatite (HAp) ceramics---Understanding the role of surface charge, wettability and dopants on physical, mechanical and biological properties. [D] . Bodhak, Subhadip. 2010

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6. Novel reversibly switchable wettability of superhydrophobic–superhydrophilic surfaces induced by charge injection and heating [O] . Xiangdong Ye, Junwen Hou, Dongbao Cai 2019

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7. The role of leaf surface wetness in larval behaviour of the sorghum shoot fly, Atherigona soccata [O] . K. F. Nwanze, Y. V. R. Reddy, P. Soman 1990

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The role of surface wettability and surface charge of electrosprayed nanoapatites on the behaviour of osteoblasts.

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